Keywords
How to Cite
Abstract
Introduction: Control of congenital syphilis (CS) is a challenge for pro-fessionals and managers of Primary Health Care (PHC). Objective: To present the results of the synthesis of scientific evidences by which options for coping with CS were identified. Method: The SUPPORT to-ol suggested by the Evidence-Informed Policy Network (EVIPNet) was used to search for systematic reviews, with the identification of op-tions to confront the problem. The searches were conducted in Biblio-teca Virtual de Saúde, Cochrane Library, Embase, Health Evidence, Health Systems Evidence, Nice Evidence, Pubmed, Scopus. Results: There were 310 studies identified. After selection, we analyzed 20 systematic reviews that resulted in a set of options: 1) Expand the offer of screening test for all pregnant women and sexual partners; 2) To perform benzathine penicillin treatment for pregnant women and sexual partners with positive screening test for syphilis; 3) Develop strategies to notify sexual partners of patients with a diagnosis of sexually transmitted infections (IST); 4) Carry out health campaigns to inform the ways of preventing congenital syphilis; promote edu-cational interventions on condom use, IST prevention, and teenage pregnancy. Conclusion: It is expected that the scientific evidence pre-sented in this article may support managers and PHC professionals in the construction of health policies to confront CS.
References
2. Walker GJA. Antibiotics for syphilis diagnosed during preg-nancy. Cochrane Database of Systematic Reviews; 2001.
3. Ministério da Saúde (BR). Portaria nº 3.242, de 30 de De-zembro de 2011. Dispõe sobre o Fluxograma Laboratorial da Sífilis e a utilização de testes rápidos para triagem da sífilis. Brasília; 2011.
4. Nascimento DSF, Silva RC, Tártari DO, Cardoso EK. Re-lato da dificuldade na implementação de teste rápido para detecção de sífilis em gestantes na Atenção Básica do SUS em um município do Sul do Brasil. Rev Bras Med Fam Comu-nidade. 2018;13(40):1-8.
5. Ministério da Saúde (BR). Protocolo Clínico e Diretrizes Terapêuticas para Prevenção da Transmissão Vertical de HIV, Sífilis e Hepatites Virais. Brasília (DF); 2018.
6. Domingues RMSM, Saraceni V, Hartz ZMDA, Leal MDC. Sífilis congênita: evento sentinela da qualidade da assistên-cia pré-natal. Rev Nutr. 2013; 47(1):147–57.
7. World Health Organization. The Global elimination of con-genital syphilis: rationale and strategy for action; 2007.
8. Domingues RMSM, Leal MC. Incidência de sífilis congê-nita e fatores associados à transmissão vertical da sífilis: dados do estudo Nascer no Brasil; 2016.
9. Rocha AFB, Araújo MAL, Miranda AE, Leon RGP, Junior GBS, Vasconcelos LDPG. Management of sexual partners of pregnant women with syphilis in northeastern Brazil: a quali-tative study. BMC Health Services Research; 2019.
10. Lavis JN, Oxman AD, Lewin S, Fretheim A. SUPPORT tooll for evidence-informed health policymaking (STP). Intro-duction. Health Research Policy and Systems; 2009.
11. Vettore M. O abismo entre o saber e o fazer: a experiên-cia do município de Piripiri com o Núcleo de Evidências em Saúde no planejamento de política em saúde; 2011.
12. Shea BJ, Grimshaw JM, Wells GA, Boers M, Andersson N, Hamel C, et al. Development of AMSTAR: a measurement tool to assess the methodological quality of systematic re-views. BMC Medical Research Methodology. 2007; 7(10).
13. Shahrook S, Mori R, Ochirbat T, Gomi H. Strategies of testing for syphilis during pregnancy; 2014.
14. Harriet DG, Peeling RW, Kamb ML, Toskin I, Wi TE, Taylor MM. A systematic review and meta-analysis of studies eva-luating the performance and operational characteristics of dual point-of-care tests for HIV and syphilis; 2016.
15. Swartzendruber A, Steiner RJ, Adler MR, Kamb ML, New-man LM. Introduction of rapid syphilis testing in antenatal care: A systematic review of the impact on HIV and syphilis testing uptake and coverage; 2015.
16. Di Mario S, Say L, Lincetto O. Risk factors for stillbirth in developing countries: a systematic review of the literatu-re; 2007.
17. Hawkes S, Matin N, Broutet N, Low N. Effectiveness of interventions to improve screening for syphilis in pregnancy: a systematic review and meta-analysis; 2011.
18. Jafari Y, Peeling RW, Shivkumar S, Claessens C, Jose-ph L, Pai NP. Are Treponema pallidum Specific Rapid and Point-of-Care Tests for Syphilis Accurate Enough for Scree-ning in Resource Limited Settings? Evidence from a Meta--Analysis; 2013.
19. Rogozinska E, Kara-Newton L, Zamora JR, Khan KS. On--site test to detect syphilis in pregnancy: a systematic re-view of test accuracy studies; 2017.
20. Blencowe H, Cousens S, Kamb M, Berman S, Lawn JE. Lives Saved Tool supplement detection and treatment of syphilis in pregnancy to reduce syphilis related stillbirths and neonatal mortality. BMC Public Health; 2011.
21. Bhutta et al. Effectiveness of interventions to screen and manage infections during pregnancy on reducing still-births: a review. BMC Public Health; 2011.
22. Lauren A, Serruya S, Duran P. Gestational syphilis and stillbirth in the Americas: a systematic review and meta-analysis; 2015
23. Ferreira A, Young T, Mathews C, Zunza M, Low N. Stra-tegies for partner notification for sexually transmitted infec-tions, including HIV; 2013.
24. Mason-Jones AJ, Sinclair D, Mathews C, Kagee A, Hill-man A, Lombard C. School-based interventions for preven-ting HIV, sexually transmitted infections, and pregnancy in adolescents; 2014.
25. Moreno R, Nababan HY, Ota E, Wariki WMV, Ezoe S, Gil-mour S, Shibuya K. Structural and community-level interven-tions for increasing condom use to prevent the transmission of HIV and other sexually transmitted infections; 2014.
26. Saraceni V, Leal M do C, Hartz ZM de A. Avaliação de campanhas de saúde com ênfase na sífilis congênita: uma revisão sistemática. Rev Bras Saúde Matern Infant. 2005; 5(3):263–73.
27. Barros FPC, Sousa MF. Equidade: seus conceitos, signi-ficações e implicações para o SUS São Paulo: Saúde Soc. 2016; 25(1):9-18.
28. Sanine et al. Sífilis Congênita: avaliação em serviços de Atenção Primária do estado de São Paulo, Brasil. BIS, Bol. Inst. Saúde. 2016; 17(2):1809-7529.
This work is licensed under a Creative Commons Attribution 4.0 International License.
Copyright (c) 2019 Mariana de Sales Dias, Emiliana Maria Gaiotto, Marcia Regina Cunha, Lúcia Izumi Yasuko Nichiata