Abstract
This paper aims to present to the reader aspects of the current debate about embryonic stem cells in our country. The text was developed based on a presentation showed at the XI Annual Scientific Meeting of the Butantan Institute, held on December 3, 2009 in Sao Paulo. The article shows the steps taken so far, given in order of the scientific integration and points to the need of expanding the generation of knowledge through the establishment of networks´research
References
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Thomson JA, Itskovitz-Eldor J, Shapiro SS, Waknitz MA, Swiegiel JJ, Marshall VS, Jones JM. Embryonic stem cell lines derived from human blastocysts. Science. 1998; 282: 1145-1147.
Wagers AJ, and Weissman IL. Plasticity of Adult Stem Cells. Cell. 2004; 116:639-684.
Yamanaka S. A fresh look at iPS cells. Cell. 2009; 137:13-17.
Downing GJ and Battey Jr. JF. Technical assessment of the first 20 years of research using mouse embryonic stem cell lines. Stem Cells. 2004; 22:1168-1180.
Evans MJ, Kaufman MH Establishment in culture of pluripotential cells from mouse embryos. Nature. 1981; 292:154-156.
Grove JE, Bruscia E, Krause DS. Plasticity of Bone Marrow-derived stem cells. Stem Cells. 2004; 22:487-500.
Krause DS, Theise ND, Collector MI, Henegariu O, Hwang S, Gardner R, Neutzel S, Sharkis SJ. Multi-organ, multi-lineage engraftment by a single bone marrow-derived stem cell. Cell. 2001; 105:369-377.
Rubinstein P, Stevens CE. The New York Blood Center’s Placental/Umbilical Cord Blood Program. Experience with a ‘new’ source of hematopoietic stem cells for transplantation. Ernst Schering Res. Found. Workshop. 2001; 33:47-70.
Thomson JA, Itskovitz-Eldor J, Shapiro SS, Waknitz MA, Swiegiel JJ, Marshall VS, Jones JM. Embryonic stem cell lines derived from human blastocysts. Science. 1998; 282: 1145-1147.
Wagers AJ, and Weissman IL. Plasticity of Adult Stem Cells. Cell. 2004; 116:639-684.
Yamanaka S. A fresh look at iPS cells. Cell. 2009; 137:13-17.
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