Resumen
Este artigo tem como objetivo apresentar ao leitor aspectos da atual discussão sobre células tronco embrionárias em nosso país. O texto foi preparado com base na apresentação realizada na XI Reunião Científica Anual do Instituto Butantan, realizada em 3 de dezembro de 2009 em São Paulo. O artigo mostra os passos dados até aqui, no sentido da incorporação científica e aponta para a necessidade de se ampliar a geração de conhecimentos, mediante o estabelecimento de redes de pesquisa.
Citas
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Wagers AJ, and Weissman IL. Plasticity of Adult Stem Cells. Cell. 2004; 116:639-684.
Yamanaka S. A fresh look at iPS cells. Cell. 2009; 137:13-17.
Downing GJ and Battey Jr. JF. Technical assessment of the first 20 years of research using mouse embryonic stem cell lines. Stem Cells. 2004; 22:1168-1180.
Evans MJ, Kaufman MH Establishment in culture of pluripotential cells from mouse embryos. Nature. 1981; 292:154-156.
Grove JE, Bruscia E, Krause DS. Plasticity of Bone Marrow-derived stem cells. Stem Cells. 2004; 22:487-500.
Krause DS, Theise ND, Collector MI, Henegariu O, Hwang S, Gardner R, Neutzel S, Sharkis SJ. Multi-organ, multi-lineage engraftment by a single bone marrow-derived stem cell. Cell. 2001; 105:369-377.
Rubinstein P, Stevens CE. The New York Blood Center’s Placental/Umbilical Cord Blood Program. Experience with a ‘new’ source of hematopoietic stem cells for transplantation. Ernst Schering Res. Found. Workshop. 2001; 33:47-70.
Thomson JA, Itskovitz-Eldor J, Shapiro SS, Waknitz MA, Swiegiel JJ, Marshall VS, Jones JM. Embryonic stem cell lines derived from human blastocysts. Science. 1998; 282: 1145-1147.
Wagers AJ, and Weissman IL. Plasticity of Adult Stem Cells. Cell. 2004; 116:639-684.
Yamanaka S. A fresh look at iPS cells. Cell. 2009; 137:13-17.
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