Keywords
Differential Diagnosis
Paracoccidioidomycosis
How to Cite
Abstract
Paracoccidioidomycosis (PCM) is a neglected systemic mycosis. We report the case of a 58-year-old male patient presenting with chronic neurological symptoms and an expansive left parietal lesion associated with cervical lymphadenopathy. The radiological findings initially suggested a neoplasm. Histopathological analysis revealed granulomas containing typical multibudding yeasts, consistent with Paracoccidioides spp. Brain involvement occurs in up to 13.9% of chronic cases and may mimic neoplasms. Definitive diagnosis requires specialized clinical evaluation, based on the correlation between clinical findings and the identification of pathognomonic fungal structures.
References
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Copyright (c) 2025 Isabelle Dias de Oliveira, Luis Fernando Mesias Barrezueta, Camila Santos da Silva Ferreira, Lidia Midori Kimura, Sandra Lorente, Juliana Possato Fernandes Takahashi, Leonardo José Tadeu de Araújo