Análise comparativa entre o diagnóstico clínico da hanseníase e os exames histopatológicos realizados segundo os critérios da classificação de Madrid e a de Ridley-Jopling
Vol. 7 No. 1 (1982), Original articles
Vol. 7 No. 1 (1982)

Análise comparativa entre o diagnóstico clínico da hanseníase e os exames histopatológicos realizados segundo os critérios da classificação de Madrid e a de Ridley-Jopling

Original articles
https://doi.org/10.47878/hi.1982.v7.35596
Published 1982-06-30
René Garrido NEVES
Prof. Adjunto. Coordenador da Disciplina de Dermatologia da Universidade Federal Fluminense. Niterói - RJBrasil
Myriam Dumas HAHN
Prof. Assistente. Depto. de Patologia. Universidade Federal Fluminense. Niterói - RJ-Brasil.
Luiz Marino BECHELLI
Prof. Titular de Dermatologia da Fac. Med. de Ribeirão Preto - SP-Brasil.
Enzo MELCHIOR JR
Médico da disciplina de Dermatologia da Fac. Med. de Ribeirão Preto - SP-Brasil.
Paulo Mucio Guimarães PAGNANO
Prof. Associado da disciplina de Dermatologia, Fac. Med. Ribeirão Preto - SP-Brasil.
Nagib HADDAD
Prof. Titular do Depto. Medicina Social, Fac. Med. Ribeirão Preto - SP-Brasil.
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Keywords

Hanseniasis
Classification
Pathology
Clinical diagnosis

How to Cite

1.
NEVES RG, HAHN MD, BECHELLI LM, MELCHIOR JR E, PAGNANO PMG, HADDAD N. Análise comparativa entre o diagnóstico clínico da hanseníase e os exames histopatológicos realizados segundo os critérios da classificação de Madrid e a de Ridley-Jopling. Hansen. Int. [Internet]. 1982 Jun. 30 [cited 2024 Nov. 23];7(1):8-24. Available from: https://periodicos.saude.sp.gov.br/hansenologia/article/view/35596
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Abstract

A comparative study of the Ridley-Jopling's (RJ) and of the Congress of Madrid's (CM) pathological criteria was made in the different clinical types and groups of hanseniasis. A concordance between both criteria was found in the Indeterminate group and in the regressive phases of the Virchowian (V), Tuberculoid (T) and Reactional tuberculoid (RT) types. Clinical RT was confirmed by pathology in 81.2% of the cases according to CM, whereas 46.2% were considered "Borderline" according to RJ. Out of the 48 clinically V patients, 17 (35.4%) were “Borderline” (BL-2, BL-1 and BB), but practically all were also pathologically V according to CM. It is concluded that there is no practical convenience in the establishment of histopathological sub-groups
that do not perfectly agree with clinical criteria. The Authors stress the importance of the study of the plasmocytes in the V infiltrates, of the lymphocytes in all granulomas and of the differences in the involvement of the neural ends, specially between the T and V poles. The dyeing of lipids by the Sudan III is useful to perfectly characterize the V pole, recognize residual V structures, separate the sub-groups BT, BB and BL, help in the early diagnosis of V infiltrations and differentiate the edematous, diffuse, non-granular cytoplasmatic vacuolization of RT. — A.R.

https://doi.org/10.47878/hi.1982.v7.35596
PDF (Português (Brasil))

References

1 AZULAY, R.D. & ANDRADE, L.M.C. O valor da pesquisa de lipídio no diagnóstico dos vários tipos estruturais encontrados na lepra: estudo realizado em 1.053 casos. Arq. Serv. , Nac. Lepra, 10(1) :47-53 1952.
2 AZULAY, R.D. & ANDRADE, L.M.C. Demonstration of Mycobacterium leprae in sections in 532 cases of leprosy: comparative study between the Ziehl-Klingmiiller and the WadeFite techniques. Int. J. Lepr., 22(2) : 195-199, 1954.
3 AZULAY, R.D. & ANDRADE, L.M.C. Pesquisa do lipídio intracitoplasmá tico nas várias estruturas histológicas encontradas na lepra. An. Bras. Dem., 44(3) :181-189, 1969.
4 AZULAY, R.D. Histopathology of skin lesions in leprosy. Int. J. Lepr., 89(2):244-250, 1971.
5 BABES, V. Die Lepra. Wien. Alfred Holder, 1901. 338p.
6 BECHELLI, L.M.; HADDAD, N.; PAGNANO, P.M.G.; NEVES, R.G.; MELCHIOR, E.; FREGNAN, R.G. Double blind trials to determine the
late reactivity of leprosy patients and unaffected persons to different concentrations of armadillo lepromin in comparison to human lepromin. Int. J. Lepr., 48(2) :126-134, 1980.
7 BERNARDI, C.D.V.; FERREIRA, J.; DEL PINO, G.; BAKOS, L.; GERBASE, A.C.; GERVINI, R.L.; GUTIERRES, M. Leprosy classification for use in control programs. Hansen. Int., 6(2): — , 1981.
8 BINFORD, C.H. The histologic recognition of the early lesions of leprosy. Int. J. Lepr., 89(2) :225-230, 1971.
9 CAMPOS, J. Lipoids in the reactional tuberculoid leprosy granuloma: their diagnostic value. Int. J. Lepr., 18(2) :155-160, 1950.
10 CONVIT, J.; AVILA, J. L.; GOIHMAN, M.; PINARDI, M.E. A test for the determination of competency in clearing bacilli in leprosy patients. Bull. Hlth Org., 46(6) :821-826, 1972.
11 HARMAN, D.J. Mycobacterium leprae in muscle. Lepr. Rev., 39(4) : 197-200, 1968.
12 KLINGMIYLLER, V. Die Lepra. In: HANDBUCH der Haut-und Geschlechtskrankheiten. Berlin, Springer, 1930. v.10, pt. 2, p.546-548.
13 NEVES, R.G. A coloração de lipidios pelo Sudão III. Importância na classificação histopatológica da hanseniase. Hansen. Int., 2 (2) :135-152, 1977.
14 NEVES, R.G. O Mycobacterium leprae no músculo eretor do pêlo. Bol. Serv. Nac. Lepra, 20 (½) :17-25, 1961.
15 NEVES, R.G. & AZULAY, R.D. The importance of lipid staining in the classification of leprosy. In: INTERNATIONAL LEPROSY CONGRESS, 11, México, 1978. Transactions. Int. J. Lepr., 47(Suppl.2) : 420, 1979.
16 PORTUGAL, H. Contribution to the study of the classification of leprosy: aspect of lesions, antigenic response, and presence of microorganisms in histologic structure. Int. J. Lepr., 15(2):162-168, 1947.
17 RABELLO JR. A clinico-epidemiological classification of the forms of leprosy. Int. .1. Lepr., 5(3) :343-356, 1937.
18 RIDLEY, D.S. Bacterial indices. In: COCHRANE, R.G. & DAVEY, T.F. Leprosy in theory and practice. 2a.ed. Bristol, John Wright, 1964. p.620-622.
19 RIDLEY, D.S. & JOPLING, W.H. Classification of leprosy for research purposes. Lepr. Rev., 33(2):119-128, 1962.
20 RIDLEY, D.S. & JOPLING, W.H. Classification of leprosy according to immunity: a five-group system. Int. J. Lepr., 84(3) :255-273, 1966.
21 RIDLEY, D.S. Histological classification and the immunological of leprosy. Bull. Wld. Hlth Org., 51(5) :451-465, 1974.
22 RIDLEY, D.S. Skin biopsy in leprosy: histological interpretation and clinical application. Basle, Ciba Geigy, 1977. 57p. (Documenta Geigy).
23 RIDLEY, M.J. & RIDLEY, D.S. Staining techniques and the morphology of Mycobacterium leprae. Lepr. Rev., 42(2):88-95, 1971.
24 RIDLEY, D.S. The pathogenesis of the early skin lesion in leprosy. J. Pathol., 111(3) :191-206, 1973.
25 ROTBERG, A. La palabra "lepra" fue la causa principal del fracaso de la educación sanitaria. Rev. Leprol. Fontilles, 8(1) :11-19, 1971.
26 SOUZA, P.R. & ALAYON, F.L. Sobre a presença de lipídios nas lesões cutâneas de lepra. Rev. Bras. Leprol., 10(4) :371-381, 1942.
27 WADE, H.W. Comission de classificacion. In: CONGRESSO INTERNACIONAL DE LEPROLOGIA, 6., Madrid, 1953. Memoria. Madrid,
1953. p.75-86.
28 WADE, H.W. Demonstration of acidfast bacilli in titssue sections. Am. J. Pathol., 28(1):157-170, 1952.

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