Laboratory frequency and antimicrobial resistance of the enteropathogens bacteria isolated from infants at early childhood in the region of ABC Paulista, 2015 - 2016
DOI:
https://doi.org/10.57148/bepa.2019.v.16.37691Keywords:
Child, Outbreak, Diarrhoea, Enterobacteriacea, Antimicrobial agentAbstract
This study aimed at evaluating the profile of enteropathogens isolated from children
under 5 years of age, during the occurrence of cases of diarrhea in the institutions of four
municipalities in the State of São Paulo in 2015 and 2016. Feces samples were collected
from 107 children, 78 (72.9%) with diarrhea and 29 (27.1%) without. The employed
methodologies were copro-culture, bacterial identification and antimicrobial susceptibility
testing. Forty-six (46%) of 107 clinical samples presented growth of enteropathogens.
Enteropathogenic Escherichia coli (EPEC), enteroaggregative Escherichia coli (EAEC)
and Salmonella enterica subsp houtenae were the mostly frequent isolated from children.
Of the total number of the studied children, three of them presented co-infection with
two etiological agents: EPEC/EAEC and Salmonella enterica subsp houtenae/EAEC. The
highest occurrence among the isolated etiologic agents was EPEC (24/49, 49%), followed
by EAEC (14/49, 28.6%). Two EPEC strains belonged to the O109:H21 serotype were
sensitive to the tested antimicrobials, whereas two belonging to the O156:H1 serotype
were resistant to gentamicin and amicacin and streptomycin, respectively. Two EAEC
strains of the same serotype O80:H10 and two EAEC O15:H2 presented multi-resistance at
least to nalidixic acid, sulfamethoxazole and tetracycline. It may suggest that the children
attending three different institutions, who had clusters of cases of diarrhoea carried the
bacterial clones of EPEC or EAEC strains, because they belonged to the same serotype
and show a similar sensitivity profile. The results found in the present study are worrying
and they show that the constant antimicrobial epidemiological surveillance should be
ensured for monitoring the emergence of resistant clones, and for establishing strategies
for preventing and controlling the outbreaks and epidemics.
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Copyright (c) 2019 Andréia Moreira dos Santos Carmo, Fernanda Miranda Lima, Flávia de Paulo Daurelio, Elisa Ribeiro Mucci, Cintia Mayumi Ahagon, Luis Fernando dos Santos, Monique Ribeiro Tiba-Casas, Maria Cecilia Cergole-Novella
This work is licensed under a Creative Commons Attribution 4.0 International License.
