Risk factors for death in fully-treated tuberculosis patients: a cohort study
Keywords:
Tuberculosis., Mortality., Elderly., Body weight.Abstract
Background: Little is known about the mortality rate of patients who fully completed the treatment of tuberculosis (TB). This study aimed at determining the rate of mortality after post-discharge from TB treatment and its associated factors. Method: Retrospective cohort study was conducted in Carapicuíba city, SP. All of the patients who completed the treatment of pulmonary TB or associated with extra-pulmonary, from 2000 to 2010 period, were followed until December 31, 2012. The following variables were analyzed: sociodemographic, co-morbidities, signs and symptoms, clinics, health equipment and treatment follow-up period. The mortality rate was calculated in personyears. Log-rank test was used to built the graphs as from Kaplan-Meier method. For the death-associated factors, the adjusted proportional hazards (HRajd) were calculated by hierarchical models of multiple regression Cox. Results: 975 patients met the inclusion criteria, and 49 (5.09 %) deaths were identified (798/100,000 person-years). The associated factors with statistical significance were: age range of 45 years or older (HRajd=5.50), spontaneous presentation to treatment (HRajd=2.11), no weight gain at treatment attack phase (HRajd=2,31). Conclusions: Identifying risk groups might be benefited by medical care and specific interventions in public health services.
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Copyright (c) 2017 Amadeu Antonio Vieira Antonio Vieira, Solange Andreoni
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