Keywords
breast cancer
risk factors
brazilian population
How to Cite
Abstract
Breast cancer is the second most common malignancy in Brazilian women. It is estimated by the INCA (The Brazilian National Institute of Cancer) that 49,400 new cases will occur this year, a standardized incidence rate of 51 per 100,000 women. In South of Brazil, there is one of the highest incidences of breast cancer in the country: an estimation rate of 56,16 per 100,000 women. In this study we report the clinical and histopathological data from 142 breast cancer patients from this region. The mean age of the patients at diagnosis was 57.7 + 13.7 years, 17.6% of patients presented early menarche (up to 12 years old), 14.7% presented late menopause (after 55 years), 18.1% were nulliparous and 13.9% reported first delivery after 30 years old. Almost 40% of patients declared the use of oral contraceptives for more than 10 years, and 24% were smokers. Tumors of histological grade II and III tumors were found in 81.1% of patients. Metastases in the lymph nodes were present in 48% of the cases and tumor size bigger than 2 cm in 86%. These histopathological characteristics are indicative of a diagnosis of advanced disease. Considering that early detection is a decisive factor to prognostic determination and highly affects survival rates, epidemiological studies characterizing breast cancer patients in the different geographic regions of the country are important to improve cancer controls methods, such as the development of prevention and screening programs to the Brazilian population.
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Copyright (c) 2009 Marcia Maria Costa de Oliveira, Clarissa Torresan, Sarah Franco Vieira de Oliveira, Giovana Tardin Torrezan, Carolina Sens Abuazar, Rubens Silveira Lima, Cicero de Andrade Urban, Luciane Regina Cavalli, Enilze Maria de Souza Fonseca Ribeiro, Iglenir João Cavalli