Keywords
wildlife reservoirs
bats
canids
surveillance
How to Cite
Abstract
Human mortality from endemic canine rabies is estimated to be 55.000 deaths per year, especially in Asia and Africa. In Latin America the canine rabies was endemic until 1980, but recently had a frequency reduction of canine rabies virus and consequently in human. With the development of “Plan of Action for the Elimination of Urban Rabies” the wildlife animals has become epidemiologically important and can be a new challenge. The most common transmitters of rabies to humans were a vampire-bat Desmodus rotundus in the period 2004-2005 (68%). Besides of the three species of vampire-bats, whose the rabies virus were isolated, there are 33 other species of non-hematophagous-bat that were related infected with the same virus. Bats (order Chiroptera) and canids (order Carnivora) are recognized as wildlife reservoirs. In Northeastern Brazil, the disease have had high frequency in Cerdocyon thous (crab-eating fox) in parallel with another epidemiological cycle rabies virus in Callithrix jacchus (marmoset) which the disease distribution is unknown. The authors describe the disease's characteristics in bats and canids, the control strategies and emphasize the importance of antigenic and genetics studies as tool of epidemiological surveillance.
References
Ito M, Arai TY, Itou T et al. Genetic characterization and geographic distribution of rabies virus isolates in Brazil: identification of two reservoirs, dogs and vampire bats.Virology 2001; 284, 214-222.
Favoretto SR, Carrieri ML, Cunha EMS et al. Antigenic typing of Brazilian rabies virus samples isolated from animals and humans, 1989-2000. Rev Inst Med Trop S Paulo 2002; 44: 91-5.
Warrell MJ & Warrell DA. Rabies and other lyssavirus diseases. Lancet 2004; 363(9413):959-69.
Rupprecht CE, Hanlon AC, Hemachudha T. Rabies re-examined. Lancet Infec Dis. 2002; 2 : 327-343.
World Health Organization, Expert Consultation on Rabies. 1° Report. (Technical Report Series, 931). 2004. World Health Organization, Geneva.
Plotkin AS. Rabies. Clin Infect Dis. 2000; 30:4-12.
Tordo N, Bahloul C, Jacob Y et al. Rabies: Epidemiological tendencies and Control Tools. In: Doted b, Schudel A, Pastoret PP. Lombard M (eds). First International Conference on Rabies in Europe. Dev.Biol (Basel), Karger, 2006; 125: 3-13.
Belotto A, Leanes LF, Schneider MC et al. Overview of rabies in the Americas. Virus Res. 2005; 111(1): 5-12.
Simmons, NB. Order Chiroptera. In: Wilson DE, Reeder DM. (eds). Mammal species of the world: A taxonomic and geographic reference.3.Ed. v.1. Baltimore: Johns Hopkins University Press, 2005, p.312-529.
Peracchi AL, Lima IP, Reis NR et al. Orden Chiroptera. In: Reis, NR, Perachi AL, Pedro WA, Lima IP (eds). Mamíferos do Brasil, 1. Ed. Londrina, Paraná, 2006, p.153-230.
Carini A. Sur une grande épizootie de rage. Ann de L’Inst Pasteur 1911; 25: 843-46.
Castilho JG, Travassos Rosa ES, Mantilla A et al. Human rabies transmitted by vampire bats: antigenic and genetic characterization of rabies virus isolates from Ecuador and Brazil. In: Anais da XVII Reunión Internacional sobre avances en la investigación y control de la rabia en las Américas; 2006 oct. 15-20; Brasilia (DF). Brasil 2006.p.73.
Travassos Rosa ES, Kotait I, Barbosa TFS et al. Bat-transmitted Human Rabies Outbreaks, Brazilian Amazon. Emer Infect Dis. 2006; 8: 1197-1202.
Kotait I. Controle da raiva dos herbívoros-Vacinação. Past In Pasteur Informa 2001; 6 p.3.
Wunner WH. Rabies in Americas. Virus Res. 2005; 111: 1-4.
Childs JE. Epidemiology. In: Jackson AC, Wunner W. Rabies. San Diego: Academic Press; 2002. p.113-62.
Favi M, De Mattos CA, Yung V et al. First case of human rabies in Chile caused by an insectivorous bat virus variant. Emerg Infect Dis. 2002; 8(1): 79-81.
Cisterna D, Bonaventura R, Caillou S et al. Antigenic and molecular characterization of rabies virus in Argentina. Virus Res. 2005; 109(2): 139-47.
Souza MCAM. Infecção experimental de morcegos hematófagos Desmodus rotundus (E.Geoffroy) mantidos em cativeiro pela ingestão de sangue desfibrinado acrescentado de amostras de vírus da raiva. São Paulo; 2003 [Tese de doutorado – Faculdade de Medicina Veterinária e Zootecnia da USP
Scheffer KC. Pesquisa do vírus da raiva em quirópteros naturalmente infectados no Estado de São Paulo, Sudeste do Brasil. São Paulo; 2005 [Dissertação de Mestrado – Faculdade de Medicina Veterinária e Zootecnia da USP].
Carrieri ML, Favoretto SR, Carnieli Jr et al. Canine and feline rabies in the Espírito Santo do Pinhal city, São Paulo, transmitted by vampire bat. In: Virus: reviews and research/Sociedade Brasileira de Virologia; 2001 nov 25-28; Caldas Novas. Vol 6 supl 1.p.176.
Kotait I, Favoretto SR, Carrieri ML et al. Raiva humana causada pela variante-3 Desmodus rotundus – no Estado de São Paulo. In: Anais da XIII Reunión Internacional sobre avances en la investigación y control de la rabia en las Américas; 2002 nov 3-8; Cidade de Oaxaca (MX). Cidade de Oaxaca: 2002.p.35
Badilla X, Herra VP, Quirós L et al. Human rabies: a reemerging disease in Costa Rica? Emer Infect Dis. 2003; 9(6): 721-723.
Carnieli PJr, Brandao PE, Carrieri ML et al. Molecular epidemiology of rabies virus strains isolated from wild canids in Northeastern Brazil. Virus Res. 2006; 120(1-2): 113-120.
Bernardi F, Nadin-Davis SA, Wandeler AI et al. Antigenic and genetic characterization of rabies viruses isolated from domestic and wild animals of Brazil identifies the hoary fox as a rabies reservoir. J Gen Virol. 2005; 86: 3153-62.
Sato G, Kobayashi Y, Shoji Y et al. Molecular epidemiology of rabies from Maranhao and surrounding states in the northeastern region of Brazil. Arch Virol. 2006; 151(11): 2243-51.
Favoretto SR, De Mattos CC, Morais NB et al. Rabies in marmosets (Callithrix jacchus), Ceará, Brazil. Emerg Infect Dis. 2001; 7(6): 1062-1065.
Niezgoda M, Hanlon CA, Rupprecht CE. Animal rabies In: Jackson AC, Wunner W. Rabies. San Diego: Academic Press; 2002. p163-218.
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Copyright (c) 2007 Ivanete Kotait, Maria Luiza Carrieri, Pedro Carnieli Júnior, Juliana Galera Castilho, Rafael de Novaes Oliveira, Carla Isabel Macedo, Karin Corrêa Scheffer Ferreira, Samira M. Achkar