Abstract
Introduction: The incidence of congenital syphilis has shown a significant increase in recent years, to the point of it being considered, in several countries, as a reemerging disease. The areas in high socioeconomic vulnerability are those with the most worrying rates. Objectives: This study aimed to describe the epidemiological characteristics of congenital syphilis in cases reported in the Regional Health Care Network 3 (RRAS 3) int the state of São Paulo). Methods: Data collection was carried out in the Notifiable Diseases Information System (Sinan), through the website of the Department of Informatics of the Brazilian unified health system (Datasus), in the period from 2018 to 2022. The data analyzed were congenital syphilis, syphilis in pregnant women, maternal sociodemographic characteristics, access to prenatal care and time of diagnosis of syphilis in pregnant women. Results: Approximately 29% of pregnant women with syphilis were teenagers. 86.3% of the notified pregnant women had more than 7 prenatal consultations and the diagnosis of syphilis in the pregnant woman in more than 60% of the cases occurred during prenatal care. Only 3.6% of pregnant women with syphilis received adequate treatment. Conclusion: Confronting congenital syphilis requires deep and robust changes in the scope of primary health care, so that the deficiencies that perpetuate such problems can finally be efficiently addressed.
References
Plan of Action for the prevention and control of HIV and sexually transmitted infections 2016-2021 - PAHO/WHO | Pan American Health Organization [Internet]. www.paho.org. Available from: https://www.paho.org/en/documents/plan-action-prevention-and-control-hiv-and-sexually-transmitted-infections-2016-2021
Choudhri Y, Miller J, Sandhu J, Leon A, Aho J. Infectious and congenital syphilis in Canada, 2010–2015. Canada Communicable Disease Report [Internet]. 2018 Feb 1;44(2):43–8. Available from: https://doi.org/10.14745/ccdr.v44i02a02
Soares MAS, Aquino R. Associação entre as taxas de incidência de sífilis gestacional e sífilis congênita e a cobertura de pré-natal no Estado da Bahia, Brasil. Cadernos de Saúde Pública. 2021;37(7).
Korenromp EL, Rowley J, Alonso M, Mello MB, Wijesooriya NS, Mahiané SG, et al. Global burden of maternal and congenital syphilis and associated adverse birth outcomes—Estimates for 2016 and progress since 2012. Vellakkal S, editor. PLOS ONE. 2019 Feb 27;14(2):e0211720.
Secretaria de Vigilância em Saúde-DCCI M da S. Boletim Epidemiológico de Sífilis - Número Especial | Out. 2022 — Português (Brasil) [Internet]. www.gov.br. 2022. Available from: https://www.gov.br/saude/pt-br/centrais-de-conteudo/publicacoes/boletins/epidemiologicos/especiais/2022/boletim-epidemiologico-de-sifilis-numero-especial-out-2022/view
Ministério da Saúde [Internet]. bvsms.saude.gov.br. 2011 [cited 2023 Jun 19]. Available from: https://bvsms.saude.gov.br/bvs/saudelegis/gm/2011/prt1459_24_06_2011.html#:~:text=1
LaFond RE, Lukehart SA. Biological Basis for Syphilis. Clinical Microbiology Reviews [Internet]. 2006 Jan;19(1):29–49. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1360276/
Brasl. Ministério da Saúde S de V em SD. ATENÇÃO INTEGRAL ÀS PESSOAS COM INFECÇÕES SEXUALMENTE TRANSMISSÍVEIS (IST) [Internet]. 2022 [cited 2022 Sep 11]. Available from: http://bvsms.saude.gov.br/bvs/publicacoes/protocolo_clinico_atecao_integral_ist.pdf
Workowski KA. Sexually Transmitted Infections Treatment Guidelines, 2021. MMWR Recommendations and Reports [Internet]. 2021;70(4). Available from: https://www.cdc.gov/mmwr/volumes/70/rr/rr7004a1.htm
Satyaputra F, Hendry S, Braddick M, Sivabalan P, Norton R. The Laboratory Diagnosis of Syphilis. Humphries RM, editor. Journal of Clinical Microbiology [Internet]. 2021 Sep 20;59(10). Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8451404/
Fang J, Partridge E, Bautista G, Sankaran D. Congenital Syphilis Epidemiology, Prevention, and Management in the United States: A 2022 Update. Cureus [Internet]. 2022 Dec 27; Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9879571/
WHO. Home [Internet]. Who.int. 2018. Available from: http://www.who.int/
Oliveira V da S, Rodrigues RL, Chaves VB, Santos TS dos, Assis FM de, Ternes YMF, et al. Aglomerados de alto risco e tendência temporal da sífilis congênita no Brasil. Revista Panamericana de Salud Pública [Internet]. 2020 Aug 6;44:1. Available from: https://iris.paho.org/bitstream/handle/10665.2/52524/v44e752020.pdf?sequence=1&isAllowed=y
http://indicadoressifilis.aids.gov.br/.
Waltz MB, Máximo TV, Marinho GL, Rodrigues AT. Sífilis gestacional segundo a idade das mães. Sífilis gestacional segundo a idade das mães: ocorrências no município do Rio deJ aneiro entre 2008 e2018. 2021 Apr 6;(2179-6750).
Pastro DDOT, Farias BP, Garcia OAG, Gambichler BDS, Meneguetti DUDO, Silva R do SU da. Prenatal quality and clinical conditions of newborns exposed to syphilis. Journal of Human Growth and Development. 2019 Nov 5;29(2):249–56.
Torres PMA, Reis AR de P, Santos AST dos, Negrinho NB da S, Menegueti MG, Gir E. Fatores associados ao tratamento inadequado da sífilis na gestação: revisão integrativa. Revista Brasileira de Enfermagem [Internet]. 2022 [cited 2022 Nov 16];75(6). Available from: https://doi.org/10.1590/0034-7167-2021-0965pt
Rigo FL, Romanelli RM de C, Oliveira IP, Anchieta LM. Assistance and educational factors associated to congenital syphilis in a referral maternity: a case-control study. Revista Brasileira de Saúde Materno Infantil [Internet]. 2021 Mar;21(1):127–37. Available from: https://www.scielo.br/j/rbsmi/a/G3MQpZDHsZqkVZSpChsvPBR/?format=pdf&lang=pt
Pereira AL, Silva LR, Moni Palma LR, Moura LL, Moura MA. Impacto do grau de escolaridade e idade no diagnóstico tardio de sífilis em gestantes. Femina [Internet]. 2020 Aug 20 [cited 2022 Mar 14];563–7. Available from: https://docs.bvsalud.org/biblioref/2020/10/1122585/femina-2020-489-563-567.pdf
Macêdo VC de, Romaguera LMD, Ramalho MO de A, Vanderlei LC de M, Frias PG de, Lira PIC de. Sífilis na gestação: barreiras na assistência pré-natal para o controle da transmissão vertical. Cadernos Saúde Coletiva. 2020 Dec;28(4):518–28.
Cavalcante ANM, Araújo MAL, Nobre MA, Almeida RLF de. Factors associated with inadequate follow-up of children with congenital syphilis. Revista de Saúde Pública [Internet]. 2019 Oct 22 [cited 2022 Jan 11];53:95. Available from: http://dx.doi.org/10.11606/s1518-8787.2019053001284
Araújo LSM de, Silva DS da, Santos IMR dos, Campos JEMP, Santana JPM de, Oliveira LL de, et al. Análise epidemiológica da sífilis congênita no nordeste brasileiro. Brazilian Journal of Health Review. 2020;3(4):9638–48.
Barcelos MRB, Lima E de FA, Dutra A frank, Comerio T, Primo CC. Congenital syphilis: epidemiological analysis and sentinel event of the quality of care for the motherlnewborn binomium. J Hum Growth Dev. 2022 Jan;32:165–75.
de Sales Dias M, Maria Gaiotto E, Regina Cunha M, Izumi Yasuko Nichiata L. Síntese de evidências para políticas de saúde: enfrentamento da sífilis congênita no âmbito da atenção primária à saúde. BIS Boletim do Instituto de Saúde. 2021 Jan 15;20(2):89–95.
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