Bifenilos policlorados em soro de homens e sua relação com o nível de antígeno prostático específico
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Palavras-chave

bifenilos policlorados
antígeno prostático específico
soro sanguíneo

Como Citar

1.
Mozzaquatro J de O, Mohr S, Duarte MMMF, Costabeber IH. Bifenilos policlorados em soro de homens e sua relação com o nível de antígeno prostático específico. Rev Inst Adolfo Lutz [Internet]. 1º de fevereiro de 2012 [citado 26º de dezembro de 2024];71(2):372-7. Disponível em: https://periodicos.saude.sp.gov.br/RIAL/article/view/32437

Resumo

O objetivo do presente trabalho foi de determinar a concentração dos bifenilos policlorados (PCBs) 28, 52, 138, 153 e 180 em amostras de soro de indivíduos do sexo masculino, e de relacionar estes valores com os índices de antígeno prostático específico (APE) previamente pesquisado na população de estudo. A extração dos compostos foi realizada por hidrólise ácida, seguida da determinação e quantificação por meio de GC-μECD. Os PCBs 28 e 52 apresentaram-se abaixo do limite de quantificação em todas as amostras analisadas. Dentre os compostos detectados, o PCB 138 foi o mais frequente (75%) e de maior valor médio (2,05 ng.mL-1); o PCB 153 foi detectado em 62,50% e o PCB 180, em 54,17% das amostras. Em relação aos níveis de APE, estes não apresentaram correlação significativa com as concentrações de PCBs nas amostras analisadas. Há escassez de trabalhos de análise desses compostos em amostras de soro de indivíduos humanos realizados no Brasil. Por conseguinte, realização de estudos adicionais são sugeridos para determinar os fatores causadores dessa contaminação, bem como novas investigações sobre a influência da concentração de PCBs sobre as taxas de APE nas amostras de soro de indivíduos do sexo masculino.
https://doi.org/10.53393/rial.2012.v71.32437
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Creative Commons License
Este trabalho está licenciado sob uma licença Creative Commons Attribution 4.0 International License.

Copyright (c) 2012 Joseane de Oliveira Mozzaquatro, Susana Mohr, Marta Maria Medeiros Frescura Duarte, Ijoni Hilda Costabeber

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