Palavras-chave
Fumonisinas
métodos analítico
alimentos
rações
métodos analítico
alimentos
rações
Como Citar
1.
Machinski Junior M. Fumonisinas: Aspectos analíticos. Rev Inst Adolfo Lutz [Internet]. 30º de dezembro de 1998 [citado 4º de dezembro de 2024];57(2):73-88. Disponível em: https://periodicos.saude.sp.gov.br/RIAL/article/view/36646
Resumo
As fumonisinas, micotoxinas presentes em alimentos e rações, principalmente no milho, são produzidas por fungos do gênero Fusarium. Foi demonstrado experimentalmente que a fumonisina B' causa a leucoencefalomalácia equina (LEME), edema pulmonar em suínos (EPS) e câncer hepático em ratos, além de ser provável agente responsável pelo câncer de esôfago em humanos, como demonstram os estudos epidemiológicos realizados na África do Sul e na China. Com a finalidade de fornecer informações a respeito dos métodos empregados na determinação de fumonisinas em alimentos e rações, foi realizada uma revisão da metodologia analítica relatados na literatura científica.
Referências
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06. AZCONA-OLIVERA, J.I.; ABOUZIED, M.M.; PLATTNER, R.D.; NORRED, W.P.; PESTKA, J.J.-
Generation of antibodies reactive with fumonisins Bt' B2, and B, by using cholera toxin as the carrier-adjuvant. Appl. Environ. Microbiol., 58(1): 169-173, 1992.
07. AZCONA-OLIVERA, J.I.; ABOUZIED, M.M.; PLATTNER, R.D.; PESTKA, J.J. - Production of monoclonal antibodies to the mycotoxins fumoni-sins Bj' B2' and B3' 1. Agric. Food Chem., 40(3): 531-534, 1992.
08. BENNETT, G.A.; RICHARD, J.L. - Liquid chromatographic method for analysis of the naphthalene dicarboxaldehyde derivative of fumonisins. 1. AOAC Int., 77(2): 501-506, 1994.
09. BEZUIDENHOUT, s.c., GELDERBLOM, W.e.A.; GORST-ALLMAN, C.P.; HORAK, R.M.;
MARASAS, W.F.O.; SPITELLER, G.; VLEGGAAR, R. - Structure elucidation of the fumonisins, mycotoxins from Fusarium moniliforme. J. Chem. Soe., Chem. Commun., 11: 743-745,1988.
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11. CAWOOD, M.E.; GELDERBLOM, W.e.A.; VLEGGAAR, R.; BEHREND, Y.; THIEL, P.G.;
MARASAS, W.F.O. - Isolation of the fumonisin mycotoxins: a quantitative approach. J. Agric. Food Chem., 39(11): 1958-1962, 1991.
12. CHU, F.S.; HUANG, X.; MARAGOS, e.M. Production and characterization of anti-idiotype and anti-anti-idiotype antibodies against fumonisin B1• J. Agric. Food Chem., 43(1): 261-267, 1995.
13. CHUNG, S.H.; KIM, Y.B. - Natural occurrence of fumonisin B 1 in Korean com and rough rice. Foods Biotechn., 4(3): 216-216, 1995.
14. COLVIN, B.M.; HARRISON, L.R. - Fumonisininduced pulmonary edema and hydrothorax in suine. Mycopathol., 117: 79, 1992.
15. DAWLATANA, M.; COKER, R.D.; NAGLER, M.J.; BLUNDEN, G. - A normal phase HPTLC method for the quantitative determination of fumonisin B1 in rice. Chromatographia, 41(3/4): 187-190,1995.
16. GELDERBLOM, W.e.A.; JASKIEWICZ, K.; MARASAS, W.F.O.; THIEL, P.G.; HORAK, R.M.; VLEGGAAR, R.; KRIEK, N.P.J. - Fumonisins - novel mycotoxins with cancer-promoting activity produced by Fusarium moniliforme. Appl. Environ. Microbiol., 54(7): 1806-1811,1988.
17. GELDERBLOM, W.e.A.; KRIEK, N.P.J.; MARASAS, W.F.O.; THIEL, P.G. - Toxicity and carcinogenicity of the Fusarium moniliforme metabolite, fumonisin B1, in rats. Carcinogenesis, 12: 1247-1251, 1991.
18. HANSEN, T.J.; ZABE, N.A.; SKIPPER, P.L. - Immunoaffinity isolation of fumonisin B 1 and application to analysis in com. Abst. l06th AOAC Int. Ann. Mtg., 230, 1992. Apud: SCOTT, P.M. Fumonisins. Inte rnat. Journal Food Microbiol., 18, 257-270, 1993.
19. HOLCOMB, M.; SUTHERLAND, J.B.; CHIARELLI, M.P.; KORFMACHER, W.A.; THOMP-
SON Jr, n.c., LAY Jr, J.O.; HANKINS, L.J.; CERNIGLIA, e.E. - HPLC and FAB Mass Spectrometry analysis of fumonisins B1 and B2 produced by Fusarium moniliforme on food substrates. J. Agric. Food Chem., 41(3): 357-360, 1993.
20. HOLCOMB, M.; THOMPSON Jr, H.C.; HANKINS, L. 1. - Analysis of fumonisin B1 in rodent feed by gradient elution HPLC using precolumn derivatization with FMOC and fluorescence detection. J. Agric. Food Chem., 41(5): 764-767, 1993.
21. HOPMANS, E.C.; MURPHY, P.A. - Detection of fumonisins Bl' B2' and B3and hydrolyzed fumonisin B1 in com-containing foods. J. Agric. Food Chem., 41(10): 1655-1658, 1993.
22. JACKSON, M.A.; BENNETT, G.A. - Production of fumonisin B1 by Fusarium moniliforme NRRL 13616 in submerged culture. Appl. Environm. Microbiol., 56(8): 2296-2298, 1990.
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Copyright (c) 1998 Miguel Machinski Junior
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