Palavras-chave
dieldrin, níveis em sangue de aplicadores de aldrin
pesticidas, resíduos
inseticidas organoclorados, aldrin, dieldrin
doença ocupacional, contaminação por exposição ao aldrin
pesticidas, resíduos
inseticidas organoclorados, aldrin, dieldrin
doença ocupacional, contaminação por exposição ao aldrin
Como Citar
1.
Lara WH, Barretto HH, Varella-Garcia M. Níveis de dieldrin em sangue de aplicadores de aldrin na região de São José do Rio Preto, São Paulo. Rev Inst Adolfo Lutz [Internet]. 30º de junho de 1981 [citado 6º de maio de 2024];41(1):9-14. Disponível em: https://periodicos.saude.sp.gov.br/RIAL/article/view/36987
Resumo
Foram determinados os níveis de dieldrin no sangue de 18 lavradores profissionalmente expostos ao aldrin, tendo sido encontrados valores muito elevados (média = 0,49 fLgjml; desvio padrão 0,36 ppm), acima dos citados na literatura em casos de intoxicação. Não pôde ser detectada correlação entre o nível sangüíneo de dieldrin e o tempo de exposição ao aldri n, o intervalo entre a exposição e a coleta do sangue, a quantidade do composto empregado ou a natureza da exposição. O grau de contaminação detectado, decorrente principalmente da manipulação imprudente do pesticida, enfatiza a necessidade de medidas mais efetivas na conscientização dos aplicadores de aldrin com relação ao risco assumido, e de fiscalização pelos órgãos responsáveis.
Referências
1. ANDERSON, P.S. & WEBER, L.J. - Toxic response as a quantitative function of body size. Toxicol appl. Pharmacol., 33: 471-83, 1975.
2. BROWN, V.K.H.; HUNTER, C.G. & RICHARDSON, A. -- A blood test diagnostic of exposure to aldrin and dieldrin. Brit. J. ind. Med., 21:283-6, 1964.
3. DALE, W.E.; COPELAND, M.F. & HAYES Jr., W.J. - Chlorinated insecticides in the body fat of people in India. Buli. Wld. Hlth. Org., 33 :471-7, 1965.
4. DALE, W.E. & MILES, J.W. - Quantitative method for determination of DDT and DDT metabolites in blood serum. J. Assoc. off, anal. Chem., 53: 1287 -92, 1970.
5. HAYES, W.J. & CURLEY, A. - Storage and excretion of dieldrin and related compounds: effects of occupational exposure. Arch. environ. Hlth. 16: 155-62, 1968.
6. JAGER, K.W. - Aldrin, dieldrin, endrin & telodrin: an epidemiologieal and toxicolotrical study of a longterm occupational exposure. Amsterdam, Elsevier, 1970.
7. KAZANTZIZ, G.; McLAUGHLIN, A.I.G. & PRIOR, P.F. - Poisoning in industrial workers by the insecticide aldrín. Brit, J. indo Med., 21:46-51, 1964.
8. LITTLEFIELD, N.A. & KODELL, R.L. Influence of genetic population structure on the results of chronic toxicity studies. J. Toxicol. environ Hlth, li: 121-9, 1979.
9. RADOMSKY, J.1.; ASTOLFI, E.; DEICHMANN, W.B. & REY, A.A. - Blood levels of organochlorine pes ticides in Argentina: occupationally and nonoccupationally exposed adults, children and newborn inf'an ts. Toxicol. appl. Pharmacol., 20: 186-93, 1971.
10. RADOMSKI, J.1.; DEICHMANN, W.B.; REY, A.A. & MERKIN, T. - Human
pesticide blood levels as a measure of body burden and pesticide exposure. Toxicol. appl. Pharmacol., 20: 175-85, 1971.
11. ROBINSON, J. & HUNTER, C.G. - Organochlorine insecticides: concentrations in human blood and adipose tissue. Arch. environ. Hlth, 13 :558-63, 1966.
12. SCHVARTSMAN, S.; ALMEIDA, W.F.; VAZ, F.A.C.; CORRADINI, H.B.; PIGATI, P.; GAETA, R. & UNGARO, M.T. - Blood levels of DDT in nonoccupationally exposed mothers and newborn infants in a city in Brazil. Environ. QuaL Saf ; 3: 154-6, 1974.
13. STAIFF, D.C.; COMER, S.W.; ARMSTRONG, J.F. & WOLFE, H.R. - Exposure to the herbicide Paraqua t. Buli. environ. Contam. Toxicol., 14 :334-40, 1975.
14. WASSERMAN, M.; NOGUEIRA, D.P.; TOMATIS, L.; ATHIE, E.; WASSTRMAN, D.; DJAVAHERIAN, M. & GUTTEL, C. - Storage of organochlorine insec ticides in people of São Paulo, Brazil. Ind. Med, Surg., 41 :22-5, 1972.
15. WOLFE, H.R. & ARMSTRONG, J.F. - Exposure of formulating plan t workers to DDT. Arch. environ. Hlth, 23:169-76, 1971.
16. WOLFE, H.R.; DURHAM, W.F. & ARMSTRONG, J.F. - Exposuro of workers to pesticides. Arch. environ. Hlth, 14:622-33, 1967.
17. WOLFE, H.R.; STAIFF, D.C. & ARMSTRONG, J.F. - Exposure of pesticide
formulating plant workers to Parathion. Buli. environ. Contam. Toxicol., 20:340-3, 1978.
18. WOLFE, H.R.; STAIFF, D.C. & ARMSTRONG, J.F. - Exposure of formulating plant workers to Ethion and Malathion. Buli. environ. Contam. Toxicol., 20: 778-81, 1978.
19. WOLFE, H.R.; ARMSTRONG, J.F.; STAIFF, D.C. & COMER, S.W. - Exposure of sprayman to pesticides. Arch. environ. Hlth, 25 :29-31, 1972.
2. BROWN, V.K.H.; HUNTER, C.G. & RICHARDSON, A. -- A blood test diagnostic of exposure to aldrin and dieldrin. Brit. J. ind. Med., 21:283-6, 1964.
3. DALE, W.E.; COPELAND, M.F. & HAYES Jr., W.J. - Chlorinated insecticides in the body fat of people in India. Buli. Wld. Hlth. Org., 33 :471-7, 1965.
4. DALE, W.E. & MILES, J.W. - Quantitative method for determination of DDT and DDT metabolites in blood serum. J. Assoc. off, anal. Chem., 53: 1287 -92, 1970.
5. HAYES, W.J. & CURLEY, A. - Storage and excretion of dieldrin and related compounds: effects of occupational exposure. Arch. environ. Hlth. 16: 155-62, 1968.
6. JAGER, K.W. - Aldrin, dieldrin, endrin & telodrin: an epidemiologieal and toxicolotrical study of a longterm occupational exposure. Amsterdam, Elsevier, 1970.
7. KAZANTZIZ, G.; McLAUGHLIN, A.I.G. & PRIOR, P.F. - Poisoning in industrial workers by the insecticide aldrín. Brit, J. indo Med., 21:46-51, 1964.
8. LITTLEFIELD, N.A. & KODELL, R.L. Influence of genetic population structure on the results of chronic toxicity studies. J. Toxicol. environ Hlth, li: 121-9, 1979.
9. RADOMSKY, J.1.; ASTOLFI, E.; DEICHMANN, W.B. & REY, A.A. - Blood levels of organochlorine pes ticides in Argentina: occupationally and nonoccupationally exposed adults, children and newborn inf'an ts. Toxicol. appl. Pharmacol., 20: 186-93, 1971.
10. RADOMSKI, J.1.; DEICHMANN, W.B.; REY, A.A. & MERKIN, T. - Human
pesticide blood levels as a measure of body burden and pesticide exposure. Toxicol. appl. Pharmacol., 20: 175-85, 1971.
11. ROBINSON, J. & HUNTER, C.G. - Organochlorine insecticides: concentrations in human blood and adipose tissue. Arch. environ. Hlth, 13 :558-63, 1966.
12. SCHVARTSMAN, S.; ALMEIDA, W.F.; VAZ, F.A.C.; CORRADINI, H.B.; PIGATI, P.; GAETA, R. & UNGARO, M.T. - Blood levels of DDT in nonoccupationally exposed mothers and newborn infants in a city in Brazil. Environ. QuaL Saf ; 3: 154-6, 1974.
13. STAIFF, D.C.; COMER, S.W.; ARMSTRONG, J.F. & WOLFE, H.R. - Exposure to the herbicide Paraqua t. Buli. environ. Contam. Toxicol., 14 :334-40, 1975.
14. WASSERMAN, M.; NOGUEIRA, D.P.; TOMATIS, L.; ATHIE, E.; WASSTRMAN, D.; DJAVAHERIAN, M. & GUTTEL, C. - Storage of organochlorine insec ticides in people of São Paulo, Brazil. Ind. Med, Surg., 41 :22-5, 1972.
15. WOLFE, H.R. & ARMSTRONG, J.F. - Exposure of formulating plan t workers to DDT. Arch. environ. Hlth, 23:169-76, 1971.
16. WOLFE, H.R.; DURHAM, W.F. & ARMSTRONG, J.F. - Exposuro of workers to pesticides. Arch. environ. Hlth, 14:622-33, 1967.
17. WOLFE, H.R.; STAIFF, D.C. & ARMSTRONG, J.F. - Exposure of pesticide
formulating plant workers to Parathion. Buli. environ. Contam. Toxicol., 20:340-3, 1978.
18. WOLFE, H.R.; STAIFF, D.C. & ARMSTRONG, J.F. - Exposure of formulating plant workers to Ethion and Malathion. Buli. environ. Contam. Toxicol., 20: 778-81, 1978.
19. WOLFE, H.R.; ARMSTRONG, J.F.; STAIFF, D.C. & COMER, S.W. - Exposure of sprayman to pesticides. Arch. environ. Hlth, 25 :29-31, 1972.
Este trabalho está licenciado sob uma licença Creative Commons Attribution 4.0 International License.
Copyright (c) 1981 Walkyria H. Lara, Heloisa H.C. Barretto, Marileila Varella-Garcia
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