Keywords
epidemiology
whooping cough
pertussis
laboratory diagnosis
How to Cite
Abstract
Pertussis or whooping cough is an acute respiratory infectious disease caused by Bordetella pertussis, a small Gram-negative coccobacillus which has complex nutritional requirements. Several countries have recently reported an increase in pertussis in immunized populations, accompanied by a significant increase among adolescents and adults. In Brazil, pertussis had its epidemiological surveillance established only in 2001. This study evaluated the indices of positivity on culture method performed according to Regan & Lowe, 1997, for pertussis diagnosis in the regions enclosed by the regional laboratories of the Instituto Adolfo Lutz - São Paulo state, Brazil, from 2001 to 2005. An increase in the number of positive samples was observed since 2004, which could be due to a better identification of the disease by health workers involved on its investigation, diagnosis, and notification. According to these results, the young infants presented the highest positivity rate (age 0-6 months, 65.0%). The older age groups (adolescents and adults) showed 19.4% of positivity. These data are relevant for monitoring pertussis diagnosis and for conducting epidemiological studies in the studied regions, and also to provide support to prevention programs.References
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