Keywords
riboflavin deficiency
pregnant women
glutathione reductase
How to Cite
Abstract
In a prospective study, the riboflavin nutritional status was evaluated in pregnant women to whom varied vitamin doses were given and in women who did not receive any vitamin supplementation during gestation. Riboflavin nutritional determination was assessed by means of glutathione reductase activation coefficient (GR-AC), and the value higher than 1.5 was considered as indicative of riboflavin deficiency. The pregnant women were divided into four groups: 123 pregnant women to whom any vitamin supplementation were not given, 25 who daily received 2.5 to 3.5mg of riboflavin, 53 who were daily supplemented with 1.0 to 1.7mg of riboflavin, and 22 to whom were daily given <0.85mg of riboflavin. The women group daily supplemented with 2.5 to 3.5mg riboflavin showed the lowest riboflavin deficiency, and the other groups (64.5%) presented vitamin deficiency with GR-AC higher than 1.5. These data suggest that the vitamin concentrations found in the commercially available vitamin supplemented – preparations, as well as those found in ingested food were insufficient to provide a good nutritional status for pregnant women. These findings strongly suggest that riboflavin deficiency has in fact been a relevant public health problem in São Paulo city.
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Copyright (c) 2007 Instituto Adolfo Lutz Journal
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