Production of "Interferon" and its action in tissue cultures
Vol. 21 No. 1-2 (1961), ORIGINAL ARTICLE
Vol. 21 No. 1-2 (1961)

Production of "Interferon" and its action in tissue cultures

ORIGINAL ARTICLE
https://doi.org/10.53393/rial.1961.21.33401
Published 1961-02-01
Martha Irene Malachowska
Bolsista do Fundo de Pesquisas do Instituto Adolfo Lutz
Adela Roth
Biologista do I.A.L
Luís Florencio de Salles Gomes
Médico-chefe do Laboratório de Vírus Dermotrópicos do Instituto Adolfo Lutz
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1.
Malachowska MI, Roth A, de Salles Gomes LF. Production of "Interferon" and its action in tissue cultures. Rev Inst Adolfo Lutz [Internet]. 1961 Feb. 1 [cited 2024 Dec. 21];21(1-2):57-64. Available from: https://periodicos.saude.sp.gov.br/RIAL/article/view/33401
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Abstract

The production of "interferon" from chorioallantoic membranes infected with two influenza strains, Al/Denver/1/57, A2/Japan/305/57, and with vaccinia virus is Each batch of "interferon" was precipitated with ammonium sulphate and reprecipitated with acetone. The dried precipitates were redissolved in Earle's solution so that 0.1 ml contained 75 gamma of powder. The materials were tested in chick embryo tissue cultures; in each case inhibition of the cytopathic effect produced by the homologous and the two heterologous viruses was observed.

https://doi.org/10.53393/rial.1961.21.33401
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Copyright (c) 1961 Instituto Adolfo Lutz Journal

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