Herpes simplex virus and cytomegalovirus antibodies frequency in serum and cerebrospinal fluid from patients with Acquired Immunodeficiency Syndrome - AIDS
Vol. 50 No. 1-2 (1990), ORIGINAL ARTICLE
Vol. 50 No. 1-2 (1990)

Herpes simplex virus and cytomegalovirus antibodies frequency in serum and cerebrospinal fluid from patients with Acquired Immunodeficiency Syndrome - AIDS

ORIGINAL ARTICLE
https://doi.org/10.53393/rial.1990.50.35103
Published 1990-12-28
Maria Isabel de Oliveira
Instituto Adolfo Lutz
Suely Pires Curti
Instituto Adolfo Lutz
Mary Eiko Sakuma
Instituto Adolfo Lutz
Ana Maria Sardinha Afonso
Instituto Adolfo Lutz
Cláudia Vaz de Azevedo
Instituto Adolfo Lutz
José Leopoldo Ferreira Antunes
Instituto Adolfo Lutz
pdf (Português (Brasil))

Keywords

Herpes simplex virus
serology
cytomegalovirus
Acquired Immunodeficiency Syndrome - AIDS

How to Cite

1.
Oliveira MI de, Curti SP, Sakuma ME, Afonso AMS, Azevedo CV de, Antunes JLF. Herpes simplex virus and cytomegalovirus antibodies frequency in serum and cerebrospinal fluid from patients with Acquired Immunodeficiency Syndrome - AIDS. Rev Inst Adolfo Lutz [Internet]. 1990 Dec. 28 [cited 2025 Jan. 10];50(1-2):269-73. Available from: https://periodicos.saude.sp.gov.br/RIAL/article/view/35103
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Abstract

From january to december, 1988, 865 serum samples and 475 cerebrospinal fluid - CSF samples from patients with Acquired Immunodeficiency Syndrome - AIDS were evaluated for the presence of antibodies to Herpes simplex virus - HSV and cytomegalovirus - CMV, using, respectively, indirect immunofluorescence and complement fixation techniques. From lhe received samples, 87.4% carne from males and 65.7% carne from people aged 20 to 39 years old. 61.5% of the serum samples and 7.5% of lhe CSF samples showed HSV antibodies. Detection of CMV antibodies revealed positive results in 42.6% serum samples and 2.7% CSF samples. Comparative analysis between these serum data and the results obtained from normal population (according to medical literature) showed a diminished frequency of antibodies in the studied group (p < 0.05). The presence of specific antibodies to herpes simplex virus or cytomegalovirus in the CSF of the patients with AIDS suggests a possible infection of the Central Nervous System by these viruses.

https://doi.org/10.53393/rial.1990.50.35103
pdf (Português (Brasil))

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Copyright (c) 1990 Revista do Instituto Adolfo Lutz

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