Resistence pattern of Mycobacterium tuberculosis from São Paulo State, Brazil, 1986 to 1990
Vol. 52 No. 1-2 (1992), ORIGINAL ARTICLE
Vol. 52 No. 1-2 (1992)

Resistence pattern of Mycobacterium tuberculosis from São Paulo State, Brazil, 1986 to 1990

ORIGINAL ARTICLE
https://doi.org/10.53393/rial.1992.52.35963
Published 1992-12-30
Eny Aparecida Matheus da Silva
Instituto Adolfo Lutz - Laboratório Central e Laboratório I de Sorocaba, SP, Brasil
Moisés Palaci
Instituto Adolfo Lutz
Daisy Nakamura Sato
Instituto Adolfo Lutz - Laboratório Central e Laboratório I de Sorocaba, SP, Brasil
Maria Alice da Silva Telles
Instituto Adolfo Lutz - Laboratório Central e Laboratório I de Sorocaba, SP, Brasil
Maria da Conceição Martins
Instituto Adolfo Lutz
Moisés Palaci
Instituto Adolfo Lutz
Suely Yoko Mizuka Ueki
Instituto Adolfo Lutz
pdf (Português (Brasil))

Keywords

Antituberculosis drugs
Mycrobacterium tuberculosis
Drug resistance
Tuberculosis

How to Cite

1.
Silva EAM da, Palaci M, Sato DN, Telles MA da S, Martins M da C, Palaci M, Ueki SYM. Resistence pattern of Mycobacterium tuberculosis from São Paulo State, Brazil, 1986 to 1990. Rev Inst Adolfo Lutz [Internet]. 1992 Dec. 30 [cited 2024 May 19];52(1-2):37-40. Available from: https://periodicos.saude.sp.gov.br/RIAL/article/view/35963
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Abstract

In order to determinate the situation of antituberculosis drug resistance in the State of São Paulo, 1668 strains of Mycobacterium tuberculosis have been studied; 254 of them were obtained from sputum of patients without previous medical treatrnent and 1414 of patients during the treatment. The initial resistence rated 16.54% and the acquired resistence rated 47.45%. The Mycobacterium tuberculosis showed a isoniazid global resistence of 10.62% and rifampicin global resistence of 6.69% showing that the most important drugs used in the tuberculosis treatrnent are presenting high resistance rate. This fact is worrisome, since it can cause the treatment failure and consequently, cause difficulties to the disease control.

https://doi.org/10.53393/rial.1992.52.35963
pdf (Português (Brasil))

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Copyright (c) 1992 Instituto Adolfo Lutz Journal

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