Immunologic study of patients with leptospirosis
Vol. 41 No. 2 (1981), ORIGINAL ARTICLE
Vol. 41 No. 2 (1981)

Immunologic study of patients with leptospirosis

ORIGINAL ARTICLE
https://doi.org/10.53393/rial.1981.41.36763
Published 1981-12-30
Everaldo Costa
Hospital Couto Maia
Ivo Coelho Silva
Hospital Couto Maia
Genaro Miranda-Filho
Hospital Couto Maia
Valteli Valverde da Silva
Hospital Couto Maia
Eulólio Moreira Caldas
Universidade Federal da Bahia
Edilson Brito
Universidade Federal da Bahia
Marilena B. Sampaio
Universidade Federal da Bahia
pdf (Português (Brasil))

Keywords

leptospirosis
human
immunologic study of patients

How to Cite

1.
Costa E, Silva IC, Miranda-Filho G, Silva VV da, Caldas EM, Brito E, Sampaio MB. Immunologic study of patients with leptospirosis. Rev Inst Adolfo Lutz [Internet]. 1981 Dec. 30 [cited 2025 Jan. 10];41(2):93-100. Available from: https://periodicos.saude.sp.gov.br/RIAL/article/view/36763
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Abstract

Immunologic tests were conducted in 22 patients with lep tospirosis who had been admitted to Couto Maia Hospital, Salvador, state of Bahia, Brazil. Cutaneous allergy was disclosed through intradermal injection of 0.1 ml of a suspension of inactivated.leptospiras, 91% of the patients giving a positive reaction. Immunofluorescence tests conducted in skin biopsies made in 5 patients
as well as the pathologic picture suggested delayed type IV hypersensitivity. Electrophoresis showed increase of IgG and IgM and a reduction of serum comple-
ment Clq and C3 • Immunoelectrophoresis disclosed a reduction of pre-albumin, increase of IgM and IgG, besides a marked increase of alpha-2-macroglobulin. These findings sugest a participation of immunity mechanisms in the pathogenesis of leptospirosis.

https://doi.org/10.53393/rial.1981.41.36763
pdf (Português (Brasil))

References

1. BRITO, E. - Imunopatologia das leptospiroses. [Apresentado ao 16. 0 Congresso Brasileiro de Medicina Veterinária, Salvador, 1978.]

2. BRZYK, T. & PARNAS, J. - Die allergische Intrakutanprobe bei Leptospirose mit Leptospirin P. Zbl. Bakt. I. Abt. Orig., 206: 272-5, 1968.

3. CALDAS, E. M.; SCHONBERG, A.; SAMPAIO, M.B.; COSTA, E. & PLANK, S.J. - Teste alérgico intracutâneo para o diagnóstico de leptospirose. Arq. Esc. Med. veto Unh'. Fed. Bahia, 3:11-25, 1978.

4. COSTA, E.; CALDAS, E.M.; SAMPAIO, M.B.; PLANK, S.J. & SCHONBERG, A. -- Teste intradérmico para diagnóstico da leptospirose. Rev. méd. Bahia, 24 :43-48, 1978.

5. OBIGER, G. & SCHONBERG, A. - Del in trakutane Leptospirin-test an schuein im Rahenen der schlach ttieruntersuchung und der piersenchenbkampsung. Fleishaoirtechaft, 54:1649-50, 1974.
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Copyright (c) 1981 Instituto Adolfo Lutz Journal

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