Keywords
leptospirosis
human
immunodiagnosis
microscopic agglutination
passive hemagglutination
indirect
immunofluorescence
human
immunodiagnosis
microscopic agglutination
passive hemagglutination
indirect
immunofluorescence
How to Cite
1.
Ribeiro MA, Kawarabayashi M, Yamada LK, Takeda AK, Corrêa MOA. Immunodiagnosis of human leptospirosis. 2. Comparative study of microscopic agglutination, passive hemagglutination and indirect immunofluorescence tests. Rev Inst Adolfo Lutz [Internet]. 1981 Dec. 30 [cited 2024 May 17];41(2):135-43. Available from: https://periodicos.saude.sp.gov.br/RIAL/article/view/36770
Abstract
Tests of passive hemagglutination employing sheep red blood cells sensitized with F.polysaccharide antigen of serovar patoc and indirect immunofluorescence using the same serovar antigen were carried out in 98specimens from 38 patients suffering from leptospirosis presumably caused by serovars icierohae-morrhagiae, copenhageni, grippothyphosa or pomona. The results were compared with those obtained with microscopic agglutination test using 10 pathogenic serovars. Passive hemagglutination and indirect immunofluorescence tests were gcnus-specific, Passive hemagglutination is considered to be more appropriate for the early diagnosis of acute human leptospirosís.
References
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11. OLlVEIRA, V.J.C.; ROCHA, J.M.B.; SILVA, G.B. & CABRAL, C.L.N. - Considerações sobre o novo surto epidêmico de leptospirose humana na Grande Recife, Brasil, em 1975. Rev. Inst. Adolfo Lutz, 37:33-36, 1977.
12. ORGANIZAÇÃO MUNDIAL DE SAÚDE Group d'experts de l'OMS. Problemcsactuels des recherches sur Ia leptospirose. Moscou, 1966. Rapport. Ginêve, 1967. [Sêr. rapp. techn. n.? 380j
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14. PINTO, A.A.; SANTA ROSA, C.A.; SADAT-SUNE, T. & FLEURY, G.C. - Comparative study between complernent fixation and microscopic agglutination tests for leptospiral diagnosis. Re», Inst: Med. trop. S. Paulo, 16:28-31, 1974.
15. RIBEIRO, M.A.; KAWARABAYASHI, M. & TAKEDA, A.K. - Imunodiagnóstico da leptospirose humana. 1. Antígeno polissacarídico para a prova de hemaglutinação passiva. Re1'. lnst, Adolio Lute, 41: 127-133, 1981.
16. ROCH, P.; SRÁMKOVÁ, L. & SALÁK, J. - The agglutinating and immunofluorescent activities of antileptospiral antibodies of human sera and of immunoglobulins M and G. J. Hyg. Epidemiol. Microbiol. Immunol., Prague, 20 :341-52, 1976.
17. SANTA ROSA, C.A. - Diagnóstico laboratorial das leptospiroses. Rev, Microbiol., 1: 97-109, 1970.
18. SULZER, C.R.; GLOSSER, J.W.; ROGERS, F.; JONES, W.L. & FRIX, M. - Evaluation of an indirect hemagglutination test for the diagnosis of human leptospirosis. J.clin. Mierobiol., 2 :218-21, 1975.
19. SULZER, C.R. & JONES, W.L. - Evaluation of a hemagglutination test for human leptospirosis. Appl. Mierobiol., 26:655-7, 1973.
20. TERPSTRA, W.J.; LIGTHART, G.S. & SCHOONE, G.J. - Serodiagnosis of human leptospirosis by enzyme-Iinked-irnmunosorbent-assay (ELISA). zu. Bakt. Hyg., I. Abt. Oriç ; 247:400-5, 1980.
21. TERPSTRA, W.J.; SCHOONE, G.J. & LIGTHART, G.S. - Counterimmunoelectrophoresis in the diagnosis of human leptospirosis. Zbl. Bakt. Hyg., I. Abt. Orig., 244: 285-90, 1979.
22. TORTEN, M.; SHENBERG, E. & VAN DER HOEDEN, J. - The use of immunofluorescenee in the diagnosis of human leptospirosís by a genus-specific antigen. J. infect. tn«, 116:537-43, 1966.
23. TURNER, L.H. - Leptospirosis lI: serology. Trans. R. Soe. trop. Med. Hyg., 62:880-99, 1968.
2. AZEVEDO, R. & CORR~A, M.O.A. - Considerações em torno da epidemia de [eptospirose na cidade de Recife em 1966. Aspectos epidemiológicos, laboratoriais e clínicos. Rev. Inst. Adolfo Lutz, 28:85-111, 1968.
3. BORG-PETERSEN, C. - Experience of leptospirosis in Denmark. Proc. R. Soe. Med., 42 :714-8, 1949.
4. CALDAS, E.M.; COSTA, E. & SAMPAIO, M.B. - Leptospirose na cidade de Salvador (Brasil). Alguns aspectos clínicos e laboratoriais. Rev, Inst. Med. trop. S. Paulo, 20: 164-76, 1978.
5. CORR~A, M.O.A. - Human leptospirosis in Brasil. Int. J. Zoonosis, 2:1-9, 1975.
6. CORR~A, M.O.A.; NATALE, V.; SADATSUNE, T. & FLEURY, G.C. - Valor prático do uso da Leptospira semaranga Patoc I no diagnóstico das leptospiroses humanas. Rev. Inst; Med. trop, S. Paulo, 12:284-7, 1970.
7. CORReA, M.O.A.; VERONESI, R.; BRITO, T.; HYAKUTAKE, S.; SANTA ROSA, C.A. & EDELWEISS, E.L. - Leptospiroses. In: VERONESI, R. - Doenças infecciosas e parasitárias. 6.a ed. Rio de Janeiro, Guanabara Koogan, 1976. p. 787-803.
8. FAINE, S.; ADLER, B. & PALIT, A. Chemical, serological and biological properties of a serotype-specific polysaccharide antigen in Leptospira. Aust. J. ezp. Biol. Med. s«, 52:311-9, 1974.
9. MAGALDI, C. - Incidência, prevalência e distribuição das leptospiroses no Brasil. Arq. Hig. Saúde públ., 28:187-97, 1963.
10. MYERS, D.M. - Evaluacion de antigenos de Ia envoltura externa de Leptospira en Ias pruebas de fijacion de complemento y de hemaglutinacion para Ia leptospirosis. Boi. Ofie. sanit. panamer., 87:141-50, 1979.
11. OLlVEIRA, V.J.C.; ROCHA, J.M.B.; SILVA, G.B. & CABRAL, C.L.N. - Considerações sobre o novo surto epidêmico de leptospirose humana na Grande Recife, Brasil, em 1975. Rev. Inst. Adolfo Lutz, 37:33-36, 1977.
12. ORGANIZAÇÃO MUNDIAL DE SAÚDE Group d'experts de l'OMS. Problemcsactuels des recherches sur Ia leptospirose. Moscou, 1966. Rapport. Ginêve, 1967. [Sêr. rapp. techn. n.? 380j
13. PALIT, A. & GULASEKHARAM, J. - Genus-specific leptospiral antigen and its possible use in laboratory díagnosís. J. clin. Path., 26:7-16, 1973.
14. PINTO, A.A.; SANTA ROSA, C.A.; SADAT-SUNE, T. & FLEURY, G.C. - Comparative study between complernent fixation and microscopic agglutination tests for leptospiral diagnosis. Re», Inst: Med. trop. S. Paulo, 16:28-31, 1974.
15. RIBEIRO, M.A.; KAWARABAYASHI, M. & TAKEDA, A.K. - Imunodiagnóstico da leptospirose humana. 1. Antígeno polissacarídico para a prova de hemaglutinação passiva. Re1'. lnst, Adolio Lute, 41: 127-133, 1981.
16. ROCH, P.; SRÁMKOVÁ, L. & SALÁK, J. - The agglutinating and immunofluorescent activities of antileptospiral antibodies of human sera and of immunoglobulins M and G. J. Hyg. Epidemiol. Microbiol. Immunol., Prague, 20 :341-52, 1976.
17. SANTA ROSA, C.A. - Diagnóstico laboratorial das leptospiroses. Rev, Microbiol., 1: 97-109, 1970.
18. SULZER, C.R.; GLOSSER, J.W.; ROGERS, F.; JONES, W.L. & FRIX, M. - Evaluation of an indirect hemagglutination test for the diagnosis of human leptospirosis. J.clin. Mierobiol., 2 :218-21, 1975.
19. SULZER, C.R. & JONES, W.L. - Evaluation of a hemagglutination test for human leptospirosis. Appl. Mierobiol., 26:655-7, 1973.
20. TERPSTRA, W.J.; LIGTHART, G.S. & SCHOONE, G.J. - Serodiagnosis of human leptospirosis by enzyme-Iinked-irnmunosorbent-assay (ELISA). zu. Bakt. Hyg., I. Abt. Oriç ; 247:400-5, 1980.
21. TERPSTRA, W.J.; SCHOONE, G.J. & LIGTHART, G.S. - Counterimmunoelectrophoresis in the diagnosis of human leptospirosis. Zbl. Bakt. Hyg., I. Abt. Orig., 244: 285-90, 1979.
22. TORTEN, M.; SHENBERG, E. & VAN DER HOEDEN, J. - The use of immunofluorescenee in the diagnosis of human leptospirosís by a genus-specific antigen. J. infect. tn«, 116:537-43, 1966.
23. TURNER, L.H. - Leptospirosis lI: serology. Trans. R. Soe. trop. Med. Hyg., 62:880-99, 1968.
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Copyright (c) 1981 Instituto Adolfo Lutz Journal
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