Keywords
thymus, morfology
mice, weight development
How to Cite
Abstract
The effect of intraperitoneal injection of sub-Ietal doses of Escherichia coli endotoxin on the thymus histology and on weight were studied in young mice. Mice were distributed into twelve groups, Each group of young mice was killed at intervals of 24 hours during five days. A control group consisting of mice of the same age was inoculated with saline solution. Another control group was weighted during two months. In the first experirnent, the inoculated mice showed weight 108s in the first 48 hours and a later recovery. The thymus of these animals showed significant
alterations of weight and of histological structure. In the second control gronp, the weight loss was maintained during the observation period, despi te some reeuperation after the initial hours.
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Copyright (c) 1985 Instituto Adolfo Lutz Journal
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