Modificação do método de Turner para a determinação da rutina em medicamentos

Myrna Sabino; Emiko Ikejiri Inomata

doi:10.53393/rial.1978.38.37132

Vol. 38 No. 2 (1978), ORIGINAL ARTICLE

Vol. 38 No. 2 (1978)

Modification of Turner's method for determination of rutin in pharmaceuticals

ORIGINAL ARTICLE

https://doi.org/10.53393/rial.1978.38.37132

Published 1978-12-29

Myrna Sabino⁺⁻
Emiko Ikejiri Inomata⁺⁻

Myrna Sabino

Instituto Adolfo Lutz

Emiko Ikejiri Inomata

Instituto Adolfo Lutz

pdf (Português (Brasil))

Keywords

rutin, determination in pharmaceuticals
Turner's method, modification
vitamin P

How to Cite

1.

Sabino M, Inomata EI. Modification of Turner’s method for determination of rutin in pharmaceuticals. Rev Inst Adolfo Lutz [Internet]. 1978 Dec. 29 [cited 2024 Jul. 3];38(2):167-70. Available from: https://periodicos.saude.sp.gov.br/RIAL/article/view/37132

Abstract

É proposta modificação do Método de Turner, para a determinação da rutina em medicamentos, que consiste na substituição do solvente etanol por metariol e introdução da solução de acetato de sódio na reação com cioreto de alumínio. O objetivo é obter uma melhor dissolução da rutina e intensificar a cor amarela do complexo formado, tornando o método mais sensível.

https://doi.org/10.53393/rial.1978.38.37132

pdf (Português (Brasil))

References

1. COUCH, J. F.; NAGHSKI, J. & KREWSON, C. F. - Buckwheat as a source of rutin. Science, 103: 197-8, 1946.

2. COUCH, J. J.; NAGHSKI, J. & KREWSON, C. F. - Rutin content of Sophoro. japoniea L. J. am. chem, Soc., 74: 424-5, 1952.

3. DECHENE, E. B. - The determination of rutin in tablets. J. Am. pharm. Ass. (Sci.), 40: 93-4, 1951.

4. KREWSON, C. F.; FENSKE, JR., C. S. & NAGHSKI, J. Rutin in eucalyptus species. Am. J. Parm., 125: 117-21, 1953.

5. SHANNO, R. L. - Rutin: a new drug for the treatment of increased capillary fragility. Am. J. med Sci., 211: 539-43, 1946.

6. STROHECKER, R. & HENNING, Vitamin aS8ay: tested met.hode, Weinheim, Verlag Chemie, 1966. p. 317-21.

7. TURNER, JR., A. - Determination of rutin in buckwheat leaf meal and other plant materials: absorptiometric method. AnaL Chem., 24: 1444-5, 1952.

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