Palabras clave
cytomegalovirus (CMV)
human immunodeficiency virus (HIV)
lymphadenopathy syndrome/AIOSrelated complex (LAS/ARC)
lyrnphocyte subsets
CMV-IgG-antibody
CMV-IgMantibody
Cómo citar
Resumen
The present study investigates the number of immunoregulatory cells in 55 patients suspected of Acquired Immunodeficiency Syndrome (AIDS) associated with cytomegalovirus (CMV) infection. Patients were divided into three groups: RISK (13 cases), LAS/ARC (21 cases) and AIOS (21 cases) according to epidemiological and clinical findings and using CDC criteria. The CMV infection was suggested based on clinical and serological evaluations. No significant difference in CMV seropositivity was observed among the groups (66.7% to 77.0%), although a diminished number of cases 3 (14.3%) with CMV-IgM antibody was detected in AIOS group. Phenotypic analysis of leukocytes, lymphocytes and lymphocyte subsets was realized. The results obtained were similar between CMV-seroposítive and CMV-seronegative patients in each group studied. On the other hand, the number of T lymphocytes and T helper/inducer lymphocytes were markedly diminished in the LAS/ARC and AIOS groups. The number of T suppressorl cytotoxic lymphocytes was increased in all groups analysed. These alterations in T lymphocyte subsets are responsible for the reversal ratio observed in these patients.
Citas
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Esta obra está bajo una licencia internacional Creative Commons Atribución 4.0.
Derechos de autor 1990 Revista do Instituto Adolfo Lutz
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