Palavras-chave
Tuberculosis
Prevalence
Prisoners
Como Citar
Resumo
Human T-cell lymphotropic virus (HTLV) is a retrovirus with a worldwide presence that may influence tuberculosis (TB) pathogenesis, particularly in populations where both infections are prevalent. This cross-sectional study aimed to estimate the prevalence of HTLV-1/2 infection among inmates with TB in Mato Grosso do Sul (MS) State, Central Brazil. Male individuals with bacteriologically confirmed active TB were recruited from two major closed male penal institutions in MS State: Instituto Penal de Campo Grande (IPCG) and Estabelecimento Penal Jair Ferreira de Carvalho (EPJFC). Serum samples were screened for anti-HTLV-1/2 antibodies using enzyme-linked immunosorbent assay (ELISA), and positive samples were confirmed by HTLV-1/2 Western Blot (WB) assay. A total of 279 inmates participated in the study. Two participants (0.72%; 95% CI 0.18 –2.84) initially tested positive for anti HTLV by ELISA. One patient was confirmed to have HTLV-1 infection by WB, along with active syphilis, while the other showed an indeterminate WB result and tested positive for anti HIV and anti-HCV. Although the overall HTLV prevalence in the sample was relatively low, this study underscores the potential for HTLV and TB co-infection in high-risk populations such as inmates.
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Copyright (c) 2025 Larissa Bandeira, Marco Antonio Moreira Puga, Carolina Amianti, Maurício Antonio Pompílio , Ana Rita Coimbra Motta-Castro