Keywords
Cysticercus cellulosae
indirect immunofluorescence
passive hemagglutination
How to Cite
Abstract
The present study aimed at analyzing the results from serologic assays performed for cysticercosis diagnosis at Immunology Center of Instituto Adolfo Lutz (IAL), during the period from March 2007 to July 2010. A total of 522 blood and cerebrospinal fluid (CSF) samples were tested for detecting the specific antibodies using indirect immunofluorescence (IFA) and passive hemagglutination (PHA) assays; the frequency of positivity was 11.0% in CSF and 8.2% in serum samples. No clinical information were reported in 50% of medical requests sent to laboratory; 18.3% of CSF and 16.4% of serum samples were from patients with available data on suspected clinical neurocysticercosis. In samples from patients with suspected neurocystycercosis, the positive results were observed in 22.6% of CSF and 18.4% of serum samples. Association between the clinical suspected neurocysticercosis and the testing positivity was detected (p> 0.05). The majority analyzed samples were from São Paulo State and 16.9% of CSF and 35.9% of serum samples were sent by others Brazilian states. The Kappa agreement index between IFI and HA assays was 86%. On account of kits for diagnosing neurocysticosis in CSF samples are commercially unavailable, the in-house assays produced at IAL have been relevant for public health services.
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