Effects of milk-based formulation of pumpkin flakes and inulin on growth and development of rats after weaning
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Keywords

vitamin A
supplementation
carotenoids
physiological development

How to Cite

1.
Souza ACM de, Salgado SM, Livera AVS, Bion FM, Andrade SAC, Silveira KC da, Faro ZP de, Guerra NB. Effects of milk-based formulation of pumpkin flakes and inulin on growth and development of rats after weaning. Rev Inst Adolfo Lutz [Internet]. 2011 Feb. 1 [cited 2024 May 18];70(2):206-12. Available from: https://periodicos.saude.sp.gov.br/RIAL/article/view/32573

Abstract

The effects of a milk-based formulation of pumpkin flakes and inulin on post weaning rat growth and development of 36 male white Wister rats were evaluated. The animals were randomly divided in three groups of 12: casein experimental pattern (GC) – GM+FA and GM+FAI – modified by the addition of 6% milk-based formulation of pumpkin flakes supplemented with 3% inulin, respectively, during 28 days. We assessed the microbiological and centesimal chemical composition of pumpkin flakes, body weight gain, food intake and coefficient of food efficiency. After dissection, the liver weight and pro-vitamin A and beta-carotene levels in GC and GM + FA were registered. A significant decrease in food intake on GC: considerable body weight gain in the GM+FAI was observed, in relation to the rest of the groups, and a substantial difference between the GC and GM+FAI in relation to CEA (food coefficient). The vitamin A and beta-carotene were significantly higher in GM + FA. The results show that inulin exerts beneficial effects on the development and growth of the rats after weaning.

https://doi.org/10.53393/rial.2011.v70.32573
PDF (Português (Brasil))

References

1. Dolinsky R, Ramalho A. Deficiência de vitamina A: uma revisão atualizada. Compacta Nutr. 2003;4:1-18.

2. Fernandes ZF, Guerra NB, Diniz NMA, Salgado SM, Guerra TMM, Lopes ACS, Neta JCPS, Padilha MRF. Desenvolvimento de bebida láctea à base de flocos de abóbora. Arch Latinoam. Nutr. 1998;48:175-8.

3. Faro ZP. Aproveitamento industrial da polpa de abóboras como estratégia para o combate à hipovitaminose A [tese de doutorado]. Recife (PE): Universidade Federal de Pernambuco; 2001.

4. Kalluf VH. Desidratação da polpa de abóbora (Cucurbita moschata) e seus teores em beta-caroteno [dissertação de mestrado]. Curitiba (PR): Universidade Federal do Paraná; 2006.

5. Ambrósio CLB, Campos FACS, Faro ZP. Carotenoides como alternativa contra a hipovitaminose A. Rev Nutr. 2006;19 (2):233-43.

6. Silveira KC. Bebida à base de flocos de abóbora com inulina: características prebióticas e aceitabilidade [dissertação de mestrado]. Recife (PE): Universidade Federal de Pernambuco; 2006.

7. Rao AV, Rao LG. Carotenoids and human health. Pharmacol Res. 2007;55:207-16.

8. Sentanin MA, Rodriguez-Amaya DB. Teores de carotenoides em mamão e pêssego determinados por cromatografia líquida de alta eficiência. Ciênc Tecnol Alim. 2007;27:13-9.

9. Valtueña S, Del Rio D, Pellegrini N, Ardigò D, Franzini L, Salvatore S, et al. The total antioxidant capacity of the diet is an independent predictor of plasma ß-carotene. Eur J Clin Nutr. 2007;61:69-76.

10. Roberfroid M. Prebiotics: The concept revisited. J Nutr. 2007;137:830S-7S.

11. Madrigal L, Sangronis E. La inulina y derivados como ingredientes claves en alimentos funcionales. Arch Latinoam Nutr. 2007;57(4):387-96.

12. Castiglia-Delavaud C, Verdier E, Besle JM, Vernet J, Boirie Y, Beaufrere, et al. Net energy value of non-starch polysaccharide isolates (sugarbeet fibre and commercial inulin) and their impact on nutrient digestive utilization in healthy human subjects. Braz J Nutr. 1998;80:343–52.

13. Roberfroid MB, Delzenne NM. Dietary fructans. Ann Rev Nutr 1998;18:117-43.

14. Reeves PG. Components of the AIN-93 diets as improvement in the AIN-76ª diet. J Nutr. 1993;123:1939-51.

15. Association of Official Analytical Chemistry. Official methods of analysis of official Analytical Chemist International. Washington; 2002.

16. Rodriguez-Amaya AB. A guide to carotenoid analysis in food. Washington: International Life Sciences Institute; 1999.

17. Trumbo PR, Yates AA, Renfro-Schlicker S, Suitor C. Dietary reference intakes: revised nutritional equivalent for folate, vitamin E and provitamin A carotenoids. J Food Comp Anal. 2003;16:379-82.

18. Buchholz AC, Schoeller DA. Is a calorie a calorie? Amer J Clin Nutr. 2004;79:899S-906S.

19. Roberfroid MB. Dietary fiber, inulin, and oligofructose: a review comparing their physiological effects. Crit Rev Food Sci Nutr. 1993;33(2):103-48.

20. Brasil. Ministério da Saúde. Resolução nº 12, de 2 de janeiro de 2001. Aprova o regulamento técnico sobre padrões microbiológicos para alimentos. Diário Oficial [da] República Federativa do Brasil. [acesso 23 jan 2008]. Disponível em: [http://e-legis.bvs.br/leisref/public/showAct.php?id=144].

21. Araújo CRC, Flores H. Improved spectrophotometric vitamin A assay. Clin Chem. 1978;24(2):386.

22. Martins MC, Oliveira YP, Coitinho DC, Santos LMP. Panorama das ações de controle da deficiência de vitamina A no Brasil. Rev Nutr. 2007;20(1):5-1

23. Chagas MHC, Flores H, Campos FACS, Santana RA, Lins ECB. Teratogenia da vitamina A. Rev Bras Saude Mater Infant. 2003;3(3):247-52.

24. Ambrósio CLB. Eficácia de flocos desidratados de abóbora na prevenção e controle da carência de vitamina A [tese de doutorado]. Recife (PE): Universidade Federal de Pernambuco; 2006.

25. Angelis RC. Novos conceitos em nutrição: reflexões a respeito do elo dieta e saúde. Arq. Gastroenterol. 2001;38 (4):269-71.

26. Yeum KJ, Russel RM. Carotenoid bioavailability and bioconversion. Ann Rev Nutr. 2002;22:483-504.

27. Scott KJ, Rodriguez-Amaya D. Pro-vitamin A carotenoid conversion factors: retinol equivalents – fact or fiction? Food Chem. 2000;69:125-7.

28. Krinsky NI, Roth-Mathews MM, Welankiwar S, Sehgal KP, Lausen NCG, Russett M. The Metabolism of [14C]ß-Carotene and the Presence of Other Carotenoids in Rats and Monkeys. J Nutr. 1990;1229: 81-7.

29. O’Neill J, Plains M. The lifelong benefits of inulin and oligofructose. Cer Foods World. 2008;53:65-8.

30. American Dietetic Association. Position of the American Dietetic Association: health implications of dietary fiber. Amer Diet Assoc. 2008;108:1716-31.

31. Abrams SA, Griggin IJ, Hawthorne KM, Ellis KJ. Effect of prebiotic supplementation and calcium intake on body mass index. J Ped. 2007;151:293-8.

32. Bosscher D, Loo JV, Franck A. Inulin and oligofructose as functional ingredients to improve bone mineralization. Intern Dairy J. 2006;16:1092-7.

33. Roberfroid MB. Introducing inulin-type fructans. Braz J Nutr. 2005;93 (1):13-25.

34. Reid G, Sanders ME, Gaskins HR, Gibson GR, Mercenier A, Rastall R et al. New scientific paradigms for probiotics and prebiotics. J Clin Gastroenterol. 2003;37 (2):105-18.

35. Brasil. Ministério da Saúde. Resolução nº 18, de 30 de abril de 1999. Aprova o regulamento técnico que estabelece diretrizes básicas para análise e comprovação de propriedades funcionais ou de saúde alegadas em rotulagem de alimentos. Diário Oficial [da] República Federativa do Brasil. [acesso 23 jan 2008]. Disponível em: [http://www.anvisa.gov.br/alimentos/legis/especifica/regutec.htm].

36. Zduńczyk Z, Juśkiewicz J, Estrella I. Cecal parameters of rats fed diets containing grapefruit polyphenols and inulin as single supplements or in a combination. Nutrit. 2006;22:898–904.

37. Lobo AR, Colli C, Filisetti TMCC. Fructooligosaccharides improve bone mass and biomechanical properties in rats. Nutr Res. 2006;26:413-20.

38. Hauly MCO, Moscatto JA. Inulina e oligofructose: uma revisão sobre propriedades funcionais, efeito prebiótico e importância na indústria de alimentos. Semina: Ciênc Exat Tecnol. 2002;23:105-18.

39. Thomas S, Prabhu R, Balasubramanian KA. Retinoid metabolism in the rat small intestine. Braz J Nutr. 2005;93:59-63.

40. Wiele TV, Boon N, Possemiers S, Jacobs H, Verstraete W. Prebiotics effects of chicory inulin in the stimulator of the human intestinal microbial ecosystem. FEMS Micr Ecol. 2004;51:143-53.

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