Use of Spirulina platensis for recovering rats under protein restriction diet feeding
Vol. 69 No. 1 (2010), ORIGINAL ARTICLE
Vol. 69 No. 1 (2010)

Use of Spirulina platensis for recovering rats under protein restriction diet feeding

ORIGINAL ARTICLE
https://doi.org/10.53393/rial.2010.v69.32677
Published 2010-01-01
Nilcimelly Rodrigues Donato
Universidade Federal de Campina Grande, Centro de Educação e Saúde, Curso de Nutrição, Cuité, PB
João Andrade da Silva
Universidade Federal da Paraíba, Departamento de Nutrição, Laboratório de Nutrição Experimental, João Pessoa, PB
Maria José de Carvalho Costa
Universidade Federal da Paraíba, Departamento de Nutrição, Laboratório de Nutrição Experimental, João Pessoa, PB
Mayara Queiroga Barbosa
Universidade Federal da Paraíba, Departamento de Nutrição, Laboratório de Nutrição Experimental, João Pessoa, PB
Francisca Martins Bion
Universidade Federal de Pernambuco, Departamento de Nutrição, Recife, PE
Edvaldo Vasconcelos de Carvalho Filho
Universidade Federal do Rio Grande do Norte, Faculdade de Ciências da Saúde do Trairí, Santa Cruz, RN
Robson Cavalcante Veras
Universidade Federal da Paraíba, Departamento de Farmácia, Laboratório de Tecnologia Farmacêutica, João Pessoa, PB
Isac Almeida de Medeiros
Universidade Federal da Paraíba, Departamento de Farmácia, Laboratório de Tecnologia Farmacêutica, João Pessoa, PB
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Keywords

cyanobacterium
lipemia
histopathology
hemoparameter protein-calorie malnutrition

How to Cite

1.
Donato NR, Silva JA da, Costa MJ de C, Barbosa MQ, Bion FM, Carvalho Filho EV de, Veras RC, Medeiros IA de. Use of Spirulina platensis for recovering rats under protein restriction diet feeding. Rev Inst Adolfo Lutz [Internet]. 2010 Jan. 1 [cited 2024 Jul. 22];69(1):69-77. Available from: https://periodicos.saude.sp.gov.br/RIAL/article/view/32677
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Abstract

This investigation aims at evaluating the effects of spirulin as a protein source for recovering the nutritional status of adult male rats. Forty-eight animals were studied and divided by four groups according to the feed diet: casein control (CC) group and spirulin control (SC) group, which received balanced diet during the whole experiment; recovered casein (RC) group and recovered spirulin (RS) group, which received a protein-restriction diet for 60 days and, afterwards, they were fed with balanced diet based on casein and spirulin, respectively, for 90 days. The centesimal and microbiological composition of Spirulina platensis and animals weight gains could be evaluated. After being euthanized the animal’s liver weight and its histopathologic aspects were analyzed, besides the body fat and blood components. The spirulin used contained 59.65% of protein, 3.72% of lipids, 17.53 of fixed mineral residue and 7.81% of humidity, and showed no microorganism contamination. Significant differences on body fat and serum protein contents could not be observed among the four animal groups. Regarding the weight gains, there was no difference among the animals of groups CC and SC in different weeks of experiments numbers 1, 5, 6, 7 and from 10 to 18, but these findings were not observed among the RC and RS groups. The relative liver weight decreased in animals under protein restriction, mainly in the group RC, but no histopathological alterations could be observed, and lipid contents decreased. In conclusion, the use of Spirulina platensis for recovering rat on protein restriction diet induces a reduction of lipemia.
https://doi.org/10.53393/rial.2010.v69.32677
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