Keywords
inibidores de proteases
inibidores de tripsina
bloqueadores de carboidratos
inibidores de amilase
pâncreas
How to Cite
Abstract
Foi investigada a veiculação de inibidores de proteases, concomitante ao consumo de “faseolamina”, cuja ingestão diária e de maneira prolongada poderia estar associada ao risco no desenvolvimento de alterações morfológicas e metabólicas de pâncreas. Dez amostras foram obtidas em farmácias de manipulação no município de Uberaba – MG, as quais são comercializadas na forma de cápsulas como “faseolamina” e uma como “farinha de feijão branco”, além de amostra de farinha preparada a partir da trituração de feijões brancos (Phaseolus vulgaris) obtidos comercialmente, sem qualquer processamento. Estas amostras foram analisadas efetuando-se a determinação de atividade de inibidores de tripsina, a determinação de proteínas totais e de atividade de inibição de amilase. Todas as amostras estudadas apresentaram atividades de
inibição de tripsina, porém com baixa ou mesmo inexistente inibição de amilase; e em algumas amostras foi detectada concentração de proteínas muito inferior ao esperado. Uma vez observada a presença de atividade de inibição de tripsina em todas as amostras estudadas, e pela inexistência de níveis seguros de consumo estabelecidos para o ser humano, e ainda baseando-se nos trabalhos sobre associação de ingestão prolongada destes inibidores com alterações de atividade pancreática, o consumo destes “bloqueadores de carboidratos” deveria ser melhor controlado.
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