Evaluation of a vaccination program against poliomyelitis in São Paulo, Brazil. II. Immunity of the population before the vaccination.
, ORIGINAL ARTICLE

Evaluation of a vaccination program against poliomyelitis in São Paulo, Brazil. II. Immunity of the population before the vaccination.

ORIGINAL ARTICLE
https://doi.org/10.53393/rial.1962.22.33412
Published 1962-02-01
Roberto de Almeida Moura
Do Instituto Adolfo Lutz.
Lucy Guglielmi Campos
Do Instituto Adolfo Lutz.
Clelia H Oliveira Martinez
Do Instituto Adolfo Lutz.
Eolo de Arruda Milano
Da Divisão do Serviço do Interior da Secretaria da Saúde Pública e da AssistênciaSocial do Estado de São Paulo.
José de Toledo Piza
Da Divisão do Serviço do Interior da Secretaria da Saúde Pública e da AssistênciaSocial do Estado de São Paulo.
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1.
de Almeida Moura R, Guglielmi Campos L, H Oliveira Martinez C, de Arruda Milano E, de Toledo Piza J. Evaluation of a vaccination program against poliomyelitis in São Paulo, Brazil. II. Immunity of the population before the vaccination. Rev Inst Adolfo Lutz [Internet]. 1962 Feb. 1 [cited 2025 Jan. 10];22:81-6. Available from: https://periodicos.saude.sp.gov.br/RIAL/article/view/33412
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Abstract

Six hundred and eitheen pre-vaccination sera of a pilot vaccination program against poliomyelitis with oral (Sabin) vaccine were studied by means of neutralization tests. The vaccination was held in São Paulo, Brazil and the sampling was carefully planned by randomization. The age-limits were from less than 1 year up to four years of age. Among 618 children, 57% belong to a fairly good socieconomic group and 49.9% are male. Neutralization titer of 1:4 was considered as positive and the endpoint of each titration was determined by microscopic observations. In the group of less than 1 year of age (127 children), 58.3 % were triple negatives, 22.0%, double negatives, 14.2%, single negatives and 5.5%, triple immune. At the age of one (133 children), there were 26.3% of triple negatives and 17.3% of triple immune. At 2, 3 and 4 years of age (129, 160 and 69 children), there were respectively 8.5, 1.9 and 1.4% of triple negatives and

37.2, 74.4 and 84.1% of triple immune. The susceptibility from 0 to 3 years of age reached the 94.4% level, confirming by laboratory means previous epidemiological data.

https://doi.org/10.53393/rial.1962.22.33412
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References

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Copyright (c) 1962 Instituto Adolfo Lutz Journal

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