Keywords
esterilization, cannulae and syringes
ethylene oxide, residues, in reesterilized cannulae and syringes
cannulae (plastic, rubber)
syringes (plastic)
ethylene oxide, residues, in reesterilized cannulae and syringes
cannulae (plastic, rubber)
syringes (plastic)
How to Cite
1.
Nogueira MH, Avelar M do CQ, Barretto HH, Cardoso DP. Toxic residues in cannulas sterilized and syringes resterilized with ethylene oxide. Rev Inst Adolfo Lutz [Internet]. 1989 Jun. 30 [cited 2024 May 18];49(1):27-34. Available from: https://periodicos.saude.sp.gov.br/RIAL/article/view/36927
Abstract
Twenty three samples made up of plastic and rubber cannulae (tubes) and syringes of many sizes, reprocessed up to twenty times were analised as to ethylene oxide residues and its reaction products ethylene chloridrin and glycol ethylene which might remain even after the aeration processo The results thereafter have been compared to the limits of tolerance established by the legislation in force and showed that the reesterilization does not bring about accumulative effects from the substances in the materiaIs, with the exception ofthe 1 ml syringes.
References
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11. MARSHALL, M.B.B.S. PEARSON, F.C.; SAGONA, M.A.; LEE, W.; WATHEN, R.L.; WARD, R.A. & DOLOVICH, J. - Reations during hemodialysis caused by alIergy to ethylene oxide gas sterilization. J. Allergy clin. Immunol., 75(5):
563-67,1985.
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13. NEVENHEIN, A. - Tests measure ethylene oxide risk to hospital's central supply staff. Hospitais, 53(6): 147-50, 1979.
14. NOGUEIRA, M.H. AVELAR, M.C.Q.; COSTA, M.G.P. & SANCHES, E.L. - Estudo do nível de impregnação do ar ambiental pelo óxido de etileno na central de material esterilizado. Parte I. Enfoque, S.Paulo, 12(2): 32-5,1984. 15. Ibid. Parte 2. Enfoque, S.Paulo, 13(1): 7-11,1985.
16. RICHMOND, G.W. ABRAHAMS, R.H.; NEMENZO, J.H. & HINE, C.H. -Anevaluation ofpassible effects on health folIowing exposure to ethyle-
ne oxide. Arch. Environ. Health, 40(1) 20-5,1985.
17. RUBBOS, D. & GARDNER, J.F. - Sterilization of syringes by ethylene oxide. J. Appl. Bacteriol., 31(1): 164-9,1968.
18. INTERNATIONAL TECHNICAL INFORMATION INSTITUTE - Toxic and hazardous: industrial chemicals safety manual for handling and disposal with toxicity and hazard data. Tokio, 1979. p.225-38.
19. YONG, R.& WALSH, P.-Sterilizationofpowered surgical instruments. AORN J., 37(5): 945-75, 1983.
2. BABB, J.R.; PHELTF, M. & DOWNS, J. - Evaluation of an ethylene oxide sterilizer. J. Hosp. Infec., 3(4): 385-94, 1982.
3. BRASIL. Leis, decretos etc. - Portaria n~ 80 de 13 de fevereiro de 1986. Diário Oficial, Brasília, 14 fev. 1986. Seção I, p. 2471. Proibe a utilização de ampolas de óxido de etileno ... e apresenta no anexo I os limites máximos de resíduos em correlatos.
4. BRASIL. Ministério da Saúde - Manual de controle de infecção hospitalar. Brasília, Centro de Documentação do Ministério da Saúde, 1985. 123p.
5. BRITO FILHO, D. - Toxicologia humana. Curitiba, Litel, 1983. p. 109.
6. ERNEST, R.R. & DOYLE,J.E. - Sterilization weith gaseous ethylene oxide: a review of chemical and physical factors: Biotechnol. Bioeng.; 10: 1-31, 1968.
7. GLASER, Z.R. - Ethylene oxide: toxicology review and field study results of hospital use. Llinviron, Fathol. Toxicol., 2(5): 173-207, 1978.
8. GUESS, W.L; JONES, A.B. -Solubility ofethylene oxide in selected plasticizers. Am. J. Hosp. Pharm., 26: 180-3, 1969.
9. GUNTHER, D.A. - Permeability of packaging materiais to ethylene oxide. Bull parent. Drug Assoc., 30(3): 152-6, 1976.
10. LOVING, P.J; ALLEN, R.O. & NOSHTR, T.J. - An evaluation of the accuracy and reability of ethylene oxide diffusion badge monitors. Med. Instrum., 18(6) 3-209-17,1984.
11. MARSHALL, M.B.B.S. PEARSON, F.C.; SAGONA, M.A.; LEE, W.; WATHEN, R.L.; WARD, R.A. & DOLOVICH, J. - Reations during hemodialysis caused by alIergy to ethylene oxide gas sterilization. J. Allergy clin. Immunol., 75(5):
563-67,1985.
12. MC GLOTHLEN, G.O. & WEIDA, D.A. - Recommendation for ETO gas sterilization of airpowered surgical instruments. AORN I., 21(1):98-101,1975.
13. NEVENHEIN, A. - Tests measure ethylene oxide risk to hospital's central supply staff. Hospitais, 53(6): 147-50, 1979.
14. NOGUEIRA, M.H. AVELAR, M.C.Q.; COSTA, M.G.P. & SANCHES, E.L. - Estudo do nível de impregnação do ar ambiental pelo óxido de etileno na central de material esterilizado. Parte I. Enfoque, S.Paulo, 12(2): 32-5,1984. 15. Ibid. Parte 2. Enfoque, S.Paulo, 13(1): 7-11,1985.
16. RICHMOND, G.W. ABRAHAMS, R.H.; NEMENZO, J.H. & HINE, C.H. -Anevaluation ofpassible effects on health folIowing exposure to ethyle-
ne oxide. Arch. Environ. Health, 40(1) 20-5,1985.
17. RUBBOS, D. & GARDNER, J.F. - Sterilization of syringes by ethylene oxide. J. Appl. Bacteriol., 31(1): 164-9,1968.
18. INTERNATIONAL TECHNICAL INFORMATION INSTITUTE - Toxic and hazardous: industrial chemicals safety manual for handling and disposal with toxicity and hazard data. Tokio, 1979. p.225-38.
19. YONG, R.& WALSH, P.-Sterilizationofpowered surgical instruments. AORN J., 37(5): 945-75, 1983.
This work is licensed under a Creative Commons Attribution 4.0 International License.
Copyright (c) 1989 Instituto Adolfo Lutz Journal
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