Atividade antifúngica do citral em leveduras do gênero Candida isoladas de pacientes hospitalizados
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Palabras clave

citral
Candida sp
leveduras
fungos e infecção hospitalar

Cómo citar

1.
Ferreira TM, Silva F de S, Teodoro GR, Costa ACBP da, Maria A, Beltrame Júnior M, Khouri S. Atividade antifúngica do citral em leveduras do gênero Candida isoladas de pacientes hospitalizados. Rev Inst Adolfo Lutz [Internet]. 1 de enero de 2009 [citado 4 de diciembre de 2024];68(1):118-25. Disponible en: https://periodicos.saude.sp.gov.br/RIAL/article/view/32751

Resumen

O citral, componente do óleo essencial de Cymbopogon citratus, tem sido pesquisado para verificar sua ação antimicrobiana em bactérias e fungos. Com o objetivo de avaliar a atividade antifúngica do citral contra leveduras do gênero Candida, no presente trabalho foram avaliadas 32 amostras de Candida albicans, 25 de C. tropicalis, 20 de C. parapsilosis e 5 de C. glabrata, coletadas de pacientes hospitalizados. O citral foi testado nas concentrações de 10%, 15%, 25%, 35%, 50% e 60% (v/v), utilizando a técnica de difusão em ágar Sabouraud. A atividade antifúngica do citral foi constatada em todas as leveduras selecionadas nas concentrações ≥ 25%. Mediante os resultados obtidos, sugere-se a realização de novas pesquisas sobre citral frente às demais espécies de fungos patogênicos para conhecer as características toxicológicas e farmacológicas para que esse componente possa futuramente ser utilizado como um importante princípio ativo na produção de novos agentes antifúngicos.

https://doi.org/10.53393/rial.2009.68.32751
PDF (Português (Brasil))

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