Palabras clave
riboflavin
vitamin B2
Cómo citar
Resumen
The erythrocyte glutathione reductase (E-GR) saturation with its coenzyme flavin adenine dinucleotide (FAD) affords the nutritional status regarding the vitamin B2, as FAD proceeds from riboflavin intake. E-GR normally exhibits physiological partial saturation with its coenzyme.OBJECTIVE: To study
the maximum in vivo saturation which could be reached by increasingly oral vitamin supplementation. METHODS: Three groups of normal volunteers were given 3 mg ( group A ), 20 mg ( group B ) and 50 mg ( group C ) riboflavin daily during twenty days. The enzyme activities were assayed before and after supplementation, with and without coenzyme addition to the reagent system. RESULTS: 77%, 83% and 87% saturation were observed in the groups A, B and C respectively. CONCLUSION: Increasing in vivo
saturation was observed with increasing oral doses of riboflavin supplementation, but total saturation
was not observed even with the highest oral 50 mg riboflavin supplementaion.
Citas
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Esta obra está bajo una licencia internacional Creative Commons Atribución 4.0.
Derechos de autor 2003 Revista do Instituto Adolfo Lutz
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