Pesquisa de antígenos ABH em eritrócitos e na saliva de pacientes hansenianos
DOI:
https://doi.org/10.47878/hi.1997.v22.36454Keywords:
ABH antigens, lepros, secretor phenotypeAbstract
The few studies that have already been published about the determination of secretor phenotypes of the salivary ABH antigens of leprosy patients, have shown there isn't a significant correlation between these substances and susceptibility to the disease. In the present study 74 patients were evaluated, being 27 lepromatous, 23 tuberculoid and 24 borderline, about the presence of ABH antigens on the erythrocytes and in the saliva, by technics of agglutination reaction in tube and inhibition of agglutination. The frequence of ABO blood groups and secretor/non-secretor henotype in these patients and in the control group were: 0= 40,5%(49%); A= 41,9%(36,5%); B= 10,8%(10,9%); AB= 6,8%(3,6%); secretor= 68,9%(82,5%) and non-secretor= 31,1%(17,5%). By the analysis of the results in leprosy patients, significant difference was not observed when comparing these distribuition of ABH antigens, on the erythrocytes and in the saliva, with controle group.
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References
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1006, 1969.
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in saliva on the aggregation of Streptococcus rattus. Antonie van Leeuwenhoek, v.57, p.97107, 1990.
25.SALDANHA, S.G. ABO blood groups and salivary secretion of ABH substances among three racial groups in São Paulo city. Rev. Brasil. Genet.,v.1, p.175-186, 1982.
26.SEHGAL, V.N. DUBE, B. Secretion of blood groupspecific substances in the saliva of leprosy patients. Int. J. Leprosy, v.35, p.375-376, 1967.
27.SPICKET, S.G. Genetics and the epidemiology of leprosy. I. The incidence of leprosy. Leprosy Review, v.33, p.76-93, 1962
28.WEINER, A.S. Blood groups and disease. Lancet., p.813-816, 1962.
29.WILLIAMS, R.C., GIBBONS, R.J. Inhibition of streptococcal attachment on human buccal epithelial cells by antigenically similar salivary glycoproteins. Infect. Immun., v.11, p.711-718, 1975.
2.ARNEBERG, P., KORNSTAD, L., NORDBO, H., GJERINO, P. Less dental caries among secretors than among non-secretors of blood group sbstance.
Scand. J. Dent. Res., v.84, p.362-366, 1976.
3.BEIGUELMAN B. Sistema ABO e epidemiologia de lepra. Rev. Paul. Med., v.65, p.80-86, 1964.
4.BETH VINCENT. Técnicas aplicadas à imunohematologia eritrocitária. In. Alves de Lima, L., Callado,M. R. L., Santos, J. A. Curso de Imunohematologia.
Botucatu. Faculdade de Medicina, p. 122, 1992.
5.BRATTHALL, D., CARLEN, A. apud LIGTENBERG, A.J.M., VEERMAN, E.C.I., GRAAFF DE J., NIEUW AMERONGEN, A.V. Influence of the blood group reactive substances in saliva on the aggregation of Streptococcus rattus. Antonie van Leeuwenhoek, v.57, p.97-107, 1990.
6.CAMPS, F.E.,DODD BARBARA E., LINCOLN, P. J. Frequencies of secretors and non-secretors of ABH group substances among 1.000 alcoholic patients. Brit. Med. J., v.4, p.457-459, 1969.
7.CHEHL, S. K., JOB, C. K., HASTINGS, R. C. Transmission of leprosy in nude (nu/nu) nice using various portals of entry. XII International leprosy Congress Proceedings, New Delhi, p.522-524, 1984.
8.CLARKE C. A., EVANS D. A. P., McCONNELL R. B., SHEPPARD P. M. Secretion of blood group antigens and peptic ulcer. Brit. Med. í.,p.603-607, 1959.
9.CONGRESSO NACIONAL DE LEPROLOGIA 6º, Madrid, 1953. Memória. Madrid, Association International de lepra, 1953. 1344p.
10.CREE, I. A, SMITH, W.C.S., BECK, J.5. Serum antibody responses to mycobacteria in leprosy patients and their contacts. Leprosy Review, v.59, p.317-327, 1988.
11.DAVEY, T. F., REES, R.J.W. The nasal discharge in leprosy. Clinical and bacteriological aspects. Leprosy Review, v.45, p.121-134, 1974.
12.DOUGLAS, C.W.I. The binding of human salivary - amylase by oral strains of streptococcal bacteria. Arch. Oral Biol., v.28, p.567-573, 1983.
13.DUDLEY, J.P. Adherence of microorganisms in infections of the respiratory tract. Laryngoscope, v.92, p.68-69, 1982.
14.DUNSFORD I., BOWLEY C.C. apud SALDANHA, S.G. ABO blood groups and salivary secretion of ABH substances among three racial groups in São Paulo. Rev. Brasil. Genet., v.1, p.175-186, 1982.
15.ERCSON, T.H., PRUITT, K., WEDEL, H. The reaction of salivary substances with bacteria. J. Oral Patol., v.4, p.307-323, 1975.
16.GIBBONS, R.J., ETHERDEN, I. Comparative hydrophobicities of oral bacteria and theiradherence to salivary pellicles. Infect. Immun., v.41, p.1190- 1196, 1983.
17.GIBBONS, R.J., QURESHI, J.V. Selective binding of blood group-reactive salivary mucins by Streptococcus mutans and other oral organisms. Infect. Immun., v.22, p.665-671, 1978.
18.GLYNN, L. E., HOLBOROW E. J. Blood groups and their secretion in rheumatic fever. Rheumatology, v.2, p.113-130, 1969.
19. J A C O B S ON , S . H . , L OMB E R G , H . Overrepresentation of blood group non-secretors in adults with renal scarring. Scand. I. Urol . Nephrol.. v.24, p.145-150, 1990.
20. KALLENIUS, G., SVENSON, S.B., MÖLLBY, R., CEDERGREN, B., HULTBERG, H., WINBERG, J. Structure of carbohidrate part of receptor on human uroepithelial cells for pyelone- phritogenic Escherichia colt. Lancet. p.604-606, 1981.
21.MANDEL, I.D., In defence of the oral cavity. pp 4 7 3 - 4 9 1 In : KLEINBERG I , El l i s o n A.S. , MANDEL I.D. Saliva and dental caries (a special
supplemment to Microbiology Abstracts). Information Retrieval. Inc, Washington DC. 1979.
22. MARCUS D.M. The ABO and Lewis blood-group system. Immunochemistry, genetics and relation to human disease. N. Engl. J. Med., v.280, p.994-
1006, 1969.
23 .MOURANT , A . E . , KOP EC , A .C. & DOMA - MIEWSKA-SOBEZA, K. The blood groups and other polymorphic systems. Oxford University Press, 1978.
24.POLLOCK apud LIGTEMBERG, A.J.M., VEERMAN, E.C.I., GRAAFF, J. NIEUW AMERONGEN, A.V. Influence of the blood group reactive substances
in saliva on the aggregation of Streptococcus rattus. Antonie van Leeuwenhoek, v.57, p.97107, 1990.
25.SALDANHA, S.G. ABO blood groups and salivary secretion of ABH substances among three racial groups in São Paulo city. Rev. Brasil. Genet.,v.1, p.175-186, 1982.
26.SEHGAL, V.N. DUBE, B. Secretion of blood groupspecific substances in the saliva of leprosy patients. Int. J. Leprosy, v.35, p.375-376, 1967.
27.SPICKET, S.G. Genetics and the epidemiology of leprosy. I. The incidence of leprosy. Leprosy Review, v.33, p.76-93, 1962
28.WEINER, A.S. Blood groups and disease. Lancet., p.813-816, 1962.
29.WILLIAMS, R.C., GIBBONS, R.J. Inhibition of streptococcal attachment on human buccal epithelial cells by antigenically similar salivary glycoproteins. Infect. Immun., v.11, p.711-718, 1975.
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1997-11-30
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Silva EA, Rúbio EM, Ura S. Pesquisa de antígenos ABH em eritrócitos e na saliva de pacientes hansenianos. Hansen. Int. [Internet]. 1997 Nov. 30 [cited 2024 May 18];22(2):44-9. Available from: https://periodicos.saude.sp.gov.br/hansenologia/article/view/36454
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This journal is licensed under a Creative Commons Attribution 4.0 International License.
