CLINICAL, EPIDEMIOLOGICAL AND IMMUNOLOGICAL STUDY TO AMERICAN TEGUMENTARY LEISHMANIASIS IN A DERMATOLOGY REFERENCE CENTER

Authors

  • Fernanda Freitas de Brito Medicas do 3º ano do Programa de Residência em Dermatologia, Instituto Lauro de Souza Lima, Bauru.
  • Ana Cecilia Versiane Duarte Pinto Medicas do 3º ano do Programa de Residência em Dermatologia, Instituto Lauro de Souza Lima, Bauru.
  • Maria Lopes Lamenha Lins Cavalcante Medicas do 3º ano do Programa de Residência em Dermatologia, Instituto Lauro de Souza Lima, Bauru.
  • Gardênia Viana da Silva Medica 2º ano do Programa de Especialização em Dermatologia, Instituto Lauro de Souza Lima, Bauru.
  • Patrick Alexander Wachholz Departamento de Saúde Pública, Faculdade de Medicina de Botucatu, UNESP - Universidade Estadual Paulista, Botucatu -Sao Paulo – Brazil.
  • Dejair Caitano do Nascimento Pesquisador Científico, Instituto Lauro de Souza Lima, Bauru - Sao Paulo - Brazil.

DOI:

https://doi.org/10.47878/hi.2015.v40.35004

Keywords:

Leishmaniasis, Epidemiology, Diagnosis, Fluorescent Antibody Technique, Montenegro skin test

Abstract

Introduction: American cutaneous leishmaniasis (ACL) is an infectious disease caused by protozoa of the genus Leishmania. World leishmaniasis is an important endemic disease and public healthproblem in developing countries. Methods: We conducted a retrospective, descriptive and analytical cross-sectional study of 34 patients diagnosed with ACL. Statistical analysis was performed using the nonparametric Spearman’s test. Results: The gender involved was male (68%) and female (32%); the age range of 1 to 92 years old. The most common clinical manifestations were localized cutaneous form (79.5%) and the ulcers (56%).The face was main affected area (44%) and the minor time from onset of symptoms to consultation was 10 months (68%) of patients. Montenegro skin test (MST) was performed in 29 patients, being positive in (89.6%) and the indirect immunofluorescence (IIF) in only 16 patients, being positive in 13. The age and the duration of the disease were significantly associated with MST. Conclusions: It was not observed the IFI association with the patient’s age and disease duration. The treatment was in most cases, meglumine antimoniate (71%), followed Pentamidine (17%). The results demonstrated that the serological tests constitute an auxiliary tool and the correlations with clinical and histopathological
findings are essential.

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References

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Published

2015-06-30

How to Cite

1.
Brito FF de, Pinto ACVD, Cavalcante MLLL, Silva GV da, Wachholz PA, Nascimento DC do. CLINICAL, EPIDEMIOLOGICAL AND IMMUNOLOGICAL STUDY TO AMERICAN TEGUMENTARY LEISHMANIASIS IN A DERMATOLOGY REFERENCE CENTER. Hansen. Int. [Internet]. 2015 Jun. 30 [cited 2024 May 19];40(1):17-24. Available from: https://periodicos.saude.sp.gov.br/hansenologia/article/view/35004

Issue

Vol. 40 No. 1 (2015)

Section

Artigos de investigação científica

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This journal is licensed under a Creative Commons Attribution 4.0 International License.

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