Clofazimina
o que a tuberculose pode ensinar para a hanseníase?
DOI:
https://doi.org/10.47878/hi.2020.v45.37258Resumo
A clofazimina, um corante riminofenazínico, sintetizado, por BARRY et al, em 1957, apresenta atividade antimicobacteriana e foi inicialmente empregada no tratamento de tuberculose. A atividade antimicobacteriana, contra o M. tuberculosis, in vitro foi muito efetiva. Entretanto, estudos experimentais em camundongos e como monoterapia, sua atividade foi considerada mal sucedida, para M. tuberculosis e M. leprae.
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Copyright (c) 2020 Dejair Caitano do Nascimento
Este trabalho está licenciado sob uma licença Creative Commons Attribution 4.0 International License.
Este periódico está licenciado sob uma Creative Commons Attribution 4.0 International License.