Expressão das proteínas p27 e p19 de vírus de leucose aviária em células não infectadas de galinha, pato e marreco
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Palavras-chave

Retrovírus
vírus endógeno
expressão de vírus endógenos
RIA

Como Citar

1.
Souza-Felippe JMM de, Higuchi T. Expressão das proteínas p27 e p19 de vírus de leucose aviária em células não infectadas de galinha, pato e marreco. Rev Inst Adolfo Lutz [Internet]. 29º de dezembro de 1989 [citado 19º de junho de 2024];49(2):169-78. Disponível em: https://periodicos.saude.sp.gov.br/RIAL/article/view/36952

Resumo

Células animais normais, não infectadas, apresentam uma característica única; a presença em seu genoma de genes (provirus) idênticos ou estritamente relacionados a retrovirus exógenos infecciosos. O nível de expressão destes genes varia de indivíduo para indivíduo: do silêncio completo até a produção de partículas virais, Proteínas de vírus endógenos e exógenos foram purificadas a partir de vírus sonicados e passados em coluna de Sepharose 6B saturada com GuHCI 6M. A presença de equivalentes dos antígenos p27 e p 19 foi analisada por radioimunoensaio. A presença de componentes de vírus endógenos foi investigada em CEF, coração, cérebro, músculo de asa e músculo de coxa de galinha, codorna e marreco. A função ou significado destas proteínas é desconhecida. Fatores ambientais, hormonais e imunológicos necessitam ser estudados.

https://doi.org/10.53393/rial.1989.49.36952
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Este trabalho está licenciado sob uma licença Creative Commons Attribution 4.0 International License.

Copyright (c) 1989 Júlia Maria Martins de Souza-Felippe, Tomoko Higuchi

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