Keywords
epidemiology
direct microscopic examination
laboratory diagnosis
How to Cite
Abstract
Paracoccidioidomycosis (PCM),an autochthonous disease from Latin America,is a systemic disease caused by a dimorfic fungus Paracoccidioides brasiliensis. It is supposed that this microorganism infects hosts when conidia in aerosol form are inhaled by individuals, causing primary acute, subacute,or even chronic lung infection. In order to give evidence of the significance in diagnosing PCM by means of direct microscopic examination, which is of low cost, and easy to perform assay, a study was carried out analyzing clinical samples from IAL Regional Laboratories Network collected during the period from January 1996 to December 2002. A total of 3,807 clinical samples from lung, and 25 extra-pulmonary clinical samples were prepared by conventional procedures. Significant quantity of exam request forms with incomplete data on patient age, profession,and birthplace was observed. Additionally, samples from male patients were more frequently requested for PCM diagnosis than from female subjects. Positive lung samples were detected in 4%, being predominantly from male patient aged from 31 to 70 years old. Positive extra-lung samples were also detected, which demonstrated the presence of this disease in other organs. Although PCM mortality rate have still been increasing in Brazil, due to systemic mycosis, PCM has not included among diseases for compulsory notification yet. PCM has still been a focus of Public Health attention even 98 years have passed since the first description was made by the investigator Adolfo Lutz.
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Copyright (c) 2006 Instituto Adolfo Lutz Journal
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