Immunoglobulin deposits in Erythema Nodosum Leprosum (ENL) JOSEPHINE ANTHON
v. 3 n. 1 (1978), Artigos originais
v. 3 n. 1 (1978)

Immunoglobulin deposits in Erythema Nodosum Leprosum (ENL) JOSEPHINE ANTHON

Artigos originais
https://doi.org/10.47878/hi.1978.v3.35637
Publicado 30-06-1978
JOSEPHINE ANTHONY
Senior Research Fellow, Cellular Immunology Laboratory. Department of Anatomy All-India Institute of Medical Sciences, New Delhi-110016, India.
M. C. VAIDYA
Associate Professor, Cellular Immunology Laboratory, Department of Anatomy, All-India Institute of Medical Sciences, New Delhi-110016, India.
A. DASGUPTA
Assistant Professor, Immunology Division, Department of Microbiology, All-India Institute of Medical Sciences, New Delhi-110016, India.
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Palavras-chave

Hanseniasis
ENL reaction
Immunology
Immunofluorescence

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1.
ANTHONY J, VAIDYA MC, DASGUPTA A. Immunoglobulin deposits in Erythema Nodosum Leprosum (ENL) JOSEPHINE ANTHON. Hansen. Int. [Internet]. 30º de junho de 1978 [citado 13º de novembro de 2024];3(1):12-7. Disponível em: https://periodicos.saude.sp.gov.br/hansenologia/article/view/35637
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Resumo

Erythema Nodosum Leprosum (ENL) skin lesions observed by fluorescence microscopy were found to contain immune complexes. While biopsies taken from at least seven ENL lesions contained deposits of immunoglobulin in their vessel walls, twelve of the lesions contained such deposits in the perivascular cell infiltrate. However, immunoglobulin deposits were observed in the dermis of all 25 ENL lesions studied. On the basis of localization of these fluorescent deposits the 25 skin lesions were classified under groups I to III and were correlated with the onset of the reaction. Control biopsies taken from the lepromatous leprosy patients without ENL were uniformly negative for immunoglobulin deposits.

https://doi.org/10.47878/hi.1978.v3.35637
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Referências

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