Immunoglobulin deposits in Erythema Nodosum Leprosum (ENL) JOSEPHINE ANTHON
Vol. 3 No. 1 (1978), Original articles
Vol. 3 No. 1 (1978)

Immunoglobulin deposits in Erythema Nodosum Leprosum (ENL) JOSEPHINE ANTHON

Original articles
https://doi.org/10.47878/hi.1978.v3.35637
Published 1978-06-30
JOSEPHINE ANTHONY
Senior Research Fellow, Cellular Immunology Laboratory. Department of Anatomy All-India Institute of Medical Sciences, New Delhi-110016, India.
M. C. VAIDYA
Associate Professor, Cellular Immunology Laboratory, Department of Anatomy, All-India Institute of Medical Sciences, New Delhi-110016, India.
A. DASGUPTA
Assistant Professor, Immunology Division, Department of Microbiology, All-India Institute of Medical Sciences, New Delhi-110016, India.
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Keywords

Hanseniasis
ENL reaction
Immunology
Immunofluorescence

How to Cite

1.
ANTHONY J, VAIDYA MC, DASGUPTA A. Immunoglobulin deposits in Erythema Nodosum Leprosum (ENL) JOSEPHINE ANTHON. Hansen. Int. [Internet]. 1978 Jun. 30 [cited 2024 Nov. 26];3(1):12-7. Available from: https://periodicos.saude.sp.gov.br/hansenologia/article/view/35637
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Abstract

Erythema Nodosum Leprosum (ENL) skin lesions observed by fluorescence microscopy were found to contain immune complexes. While biopsies taken from at least seven ENL lesions contained deposits of immunoglobulin in their vessel walls, twelve of the lesions contained such deposits in the perivascular cell infiltrate. However, immunoglobulin deposits were observed in the dermis of all 25 ENL lesions studied. On the basis of localization of these fluorescent deposits the 25 skin lesions were classified under groups I to III and were correlated with the onset of the reaction. Control biopsies taken from the lepromatous leprosy patients without ENL were uniformly negative for immunoglobulin deposits.

https://doi.org/10.47878/hi.1978.v3.35637
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References

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