Avaliação dos níveis de lipídeos, lipoproteínas, apoproteínas e o papel da lipoproteína(a) no desenvolvimento de aterosclerose e alterações fibrinolíticas nos pacientes portadores de hanseníase virchoviana

Autores

  • Dirceu Dalpino Instituto Lauro de Souza Lima - Bauru - SP
  • Luiz Alberto Magna Universidade Estadual de Campinas - UNICAMP - SP
  • Diltor Vladimir Araújo Opromolla Instituto Lauro de Souza Lima - Bauru - SP

DOI:

https://doi.org/10.47878/hi.1997.v22.36452

Palavras-chave:

Lipoproteína, aterosclerose, hanseníase

Resumo

Muitos pacientes portadores de hanseníase virchoviana, após longo tempo de evolução, apresentam alterações dérmicas muito semelhantes aos xantomas e seus exames histológicos mostram numerosos macrófagos carregados de material lipídico. Esses fatos, associados a alterações humorais dos lipídeos descritas na literatura, sugerindo alterações no metabolismo dos mesmos, levou-nos a estudos, visando a estabelecer valores médios em pacientes, utilizando-se de novas determinações lipoprotêicas e de apoproteínas muito mais precisas. A Lipoproteína(a) apresentou valor médio acima de 20 mg/dl em 64,6% dos pacientes, contra 33,3% no grupo controle. O encontro de Lipoproteína(a) aumentada em pacientes portadores de hanseníase virchoviana é importante, porque existe uma comprovada relação entre esta lipoproteína e alterações vasculares tipo ateroscleróticas e distúrbios na fibrinólise.

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30-11-1997

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Dalpino D, Magna LA, Opromolla DVA. Avaliação dos níveis de lipídeos, lipoproteínas, apoproteínas e o papel da lipoproteína(a) no desenvolvimento de aterosclerose e alterações fibrinolíticas nos pacientes portadores de hanseníase virchoviana. Hansen. Int. [Internet]. 30º de novembro de 1997 [citado 21º de junho de 2024];22(2):20-3. Disponível em: https://periodicos.saude.sp.gov.br/hansenologia/article/view/36452

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