New approach to curb the transmission of leprosy
Vol. 14 No. 1 (1989), Original articles
Vol. 14 No. 1 (1989)

New approach to curb the transmission of leprosy

Original articles
https://doi.org/10.47878/hi.1989.v14.35515
Published 1989-06-30
M.C. PRABHAKAR
University College of Pharmaceutical Sciences, Kakatiya University, Warangal 506 009, India.
A.V.N. APPA RAO
University College of Pharmaceutical Sciences, Kakatiya University, Warangal 506 009, India.
D.R. KRISHNA
University College of Pharmaceutical Sciences, Kakatiya University, Warangal 506 009, India.
T.V. RAMANAKAR
Department of Phatology, Kakatiya Medical College, Warangal 506 006, India.
P.G. RAO
Viswakaruna Dermatological Centre, Kazipet. India.
K. NARSIMHA REDDY
Leprosy Hospital, Jammikunta, India.
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Keywords

Hanseniasis
Rifampicin Nasal Drops and Sprays
Local Treatment

How to Cite

1.
PRABHAKAR M, RAO AA, KRISHNA D, RAMANAKAR T, RAO P, REDDY KN. New approach to curb the transmission of leprosy. Hansen. Int. [Internet]. 1989 Jun. 30 [cited 2024 Dec. 22];14(1):6-13. Available from: https://periodicos.saude.sp.gov.br/hansenologia/article/view/35515
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Abstract

The effect of local treatment of nose of lepromatous type of patients with different formulations of rifampicin nasal  rops/sprays was investigated in a large number of patients. The preparations were either sprayed or instilled into the nostrils after flushing the nostrils with normal saline at 370 C. It was observed that 10 mg/ml of rifampicin was effective in reducing the BI and MI to zero in nose in seven days in majority of the patients. No untoward effect was seen in any of the patients. It is suggested that nasal sprays/drops may be able to prevent the transmission of hanseniasis, as nose is recognised to be an important portal of exit of M. leprae. Further when rifampicin drops/sprays are used as soon as the diagnosis is made, the nasal deformity may be prevented. It is believed that local treatment along with systemic therapy would go a long way in controlling the transmission of hanseniasis.

https://doi.org/10.47878/hi.1989.v14.35515
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References

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