Rapidly progressive (crescentric) glomerulonephritis in erythema nodosum leprosum: case report

Pranesh Pranesh NIGAM; K.C. PANT; R.D. MUKHIJA; S.P. SHARMA; S.P. SAXENAS; Ajax KUMAR; K.K. KAPOOR; A.K. GUPTA

doi:10.47878/hi.1986.v11.35532

Authors

Pranesh Pranesh NIGAM Reader in Medicine
K.C. PANT Registrar in Medicine
R.D. MUKHIJA Professor of Skin, V.D. & Leprosy
S.P. SHARMA Reader in Pathology
S.P. SAXENAS Lecturer in Biochemistry
Ajax KUMAR Lecturer in Cardiology
K.K. KAPOOR Lecturer in Medicine
A.K. GUPTA Professor of Medicine Head, Principal & Dean

DOI:

https://doi.org/10.47878/hi.1986.v11.35532

Keywords:

Leprosy, Erythema nodosum leprosum, Glomerulonephritis

Abstract

A middle aged man (48 years) with short duration of illness (7 days) was admitted in the state of acute renal failure with erythema nodosum leprosum. He had repeated episodes of erythema nodosum leprosum in the past. His blood pressure was normal (150/80 mm Hg). During his hospital stay he was in the state of progressive anaemia (Hb = 8.8 g/dl to 7.2 g/dl), oliguria (urine out-put = 250-350 ml/day), azotaemia (blood urea = 198 mg/d1 to 218 mg/dl) and impaired renal function tests with fatal outcome. Kidneys were smooth, congested and weighing 150 g each with histological features of rapidly progressive (crescentric) glomerulonephritis, a result of immune complex deposition from recurrent erythema nodosum leprosum episodes.

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References

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