Keywords
Mitsuda's reaction
Hanseniasis
How to Cite
Abstract
Hanseniasis patients and contacts of Virchowian patients, totalizing 467 persons have been submitted to Mitsuda's reaction. These individuals have been divided into five groups: group 1 compounded of 59 persons, relatives of Virchowian patients; group 2 — 171 persons, employees of the Hospital Lauro de Souza Lima working there for more than one year; group 3 —127 hanseniasis patients in activity, Mitsuda negative; group 4 — 63 hanseniasis patients in activity, Mitsuda positive; group 5 — 47 Virchowian patients, inactive, Mitsuda negative. The analysis of the data showed that: a) hanseniasis patients, both Mitsuda positive and negative, do nor present positivity to Fernandez's reaction; b) early reaction can be observed more frequently in individuais of group 1 than in those of group 2. Mitsuda's antigen causes the reversal of Fernandez's reaction in about 30% of indirect contatcs; c) the percentage of negative Mitsuda's reactions (without induration) does not differ between groups 1 and 2, though inclinations smaller than 5mm have been as many as 10 times more frequent in individuals of group 1. A second application of the antigen in Mitsuda negative persons showed the reversal of the test in 100% of the tested subjects.
References
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