Diabetic status in leprosy
Vol. 4 No. 1 (1979), Original articles
Vol. 4 No. 1 (1979)

Diabetic status in leprosy

Original articles
https://doi.org/10.47878/hi.1979.v4.35626
Published 1979-06-30
Pranesh NIGAM
Lecturer in Medicine, Jhansi, India.
S. G. DAYAL
Lecturer in Dermato-venereology & Leprosy, Jhansi, India.
P. SRIVASTAVA
Lecturer in Biochemistry, Jhansi India.
L . D. JOSHI
Reader in Biochemistry, Jhansi, India.
B. M. GOYAL
Reader in Tuberculosis & Chest Diseases, Jhansi, India.
Brahma DUTT
Professor & Head of the Dept. of Physiology, Jhansi, India.
M. C. GUPTA
Professor & Head of the Dept. of Medicine. Jhansi, India.
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Keywords

Diabetes
Hanseniasis
Hansen's disease
Leprosy

How to Cite

1.
NIGAM P, DAYAL SG, SRIVASTAVA P, JOSHI L . D, GOYAL BM, DUTT B, GUPTA MC. Diabetic status in leprosy. Hansen. Int. [Internet]. 1979 Jun. 30 [cited 2024 Dec. 27];4(1):7-14. Available from: https://periodicos.saude.sp.gov.br/hansenologia/article/view/35626
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Abstract

The diabetic status of the local Jhansi patients (120 cases) was established before and after antileprosy treatment. Control studies were performed in normal healthy subjects (50 persons) without family history of diabetes mellitus. Random normals showed an incidence of diabetes only 2%, while leprosy patients (94 males and 26 females) had incidence of diabetic status of 14.2%. The highest incidence (19.3 %) of diabetes was in lepromatous leprosy and lowest incidence (6.4%) in tuberculoid leprosy patients. Repeated studies in leprosy after treatment showed not only clinical improvement for leprosy but also disappearance of the chemical and latent diabetes mellitus and lowering of blood sugar levels in manifest diabetes mellitus. Incidently it was noted that `diabetic status' was worse among males (82.3%) and with advancing age. Association and improvement of diabetic status with specific treatment would tentatively suggest that Mycobacterium leprae lesions are not confined to skin alone but somehow also related to carbohydrate metabolism. A careful management of the chemical and latent diabetes may help in clinical management of leprosy too.

https://doi.org/10.47878/hi.1979.v4.35626
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References

1. BEISEL, W.R.; SAWYER, W.D.; RYLL, E.D. et al. Metabolic effects of intracellular infections in man. Ann. Intern. Med., 67:744-749, 1967.
2. DHARMENDRA, M.B.B.S. Notes on Leprosy. 2.ed. Delhi, Ministry of Health, 1967.
3. DRACHMANN, R.; ROOT, R.; WOOD, W. B. Studies on the effect of experimental non-ketotic diabetes mellitus on anti-bacterial defence. In: DIABETES Mellitus: theory and practice. New York, Blackiston, 1970.
4. FAJANS, S.S. & CONN, J.W. Approach to production of diabetes mellitus by modifications of glucose tolerance test with cortisone. Diabetes, 3:296-304, 1954.
5. JOHNSON, J.E. Infection and diabetes. In: DIABETES Mellitus: theory and practice. New York, Blackiston, 1970.
6. KARAT, A.B.A.; JOB, C.K.; RAO, P.S.S. Liver in leprosy: histological and biochemical findings. Brit. Med. I., 1(5744):307-310, 1971 apud Excerpta Med. Dermatol. Venereol., 25(9): 337, 1971.
7. NIGAM, P.; GOYAL, B.M.; JOSHI, L.D.; DU TT, B.; VAJPEYI, G.N. Incidence of manifest, chemical and latent diabetes mellitus in asthma. J. Diab. Assoc. Ind., 16:89-93, 1976.
8. NIGAM, P.; GOYAL, B.M.; SAMUEL, K.C.; Study of kidney changes in leprosy. In: REGIONAL CONGRESS ON DERMATOLOGY„ 2.0 Bangkok, 1977. p.17-21
9. NIGAM, P.; GOYAL, B.M.; MISHRA, D. N.; VERMA, B.L.; JOSHI, L.D.; VAJPEYI, G.N. Diabetes mellitus in chronic bronchitis. Ind. Med. Gaz., 15:280-284, 1975.
10. NIGAM, P.; MUKHIJA, R.D.; GOYAL, B. M. Study of histo functional complex of liver in leprosy. Ind. J. Dermatol. Venereol. L eprol.. 42(5):217-222, 1976 apud Excerpta Med. Dermatol. Venereol., 32(2):136, 1978.
11. PATEL, J.C. & DHIRWANI, M.K. Incid ence of diabetes in Bombay. Ind. 1. Med. Sciences. 12:10-14, 1953.
12. ROSS, H. Clinical biochemistry and immunology in leprosy. A review. Lepr. India, 36(2):93 107, 1964.
13. TYAGI, S.P. & SEHGAL, V.N. Glucose tolerance in leprosy. Clinician, 35:431-432, 1971.
14. VAISHNAVA, H.; DIXIT, N.S.; SOLOMON, S.K. A study retrospective of hospitalised patients of diabetes mellitus in South In dia. I. Ind. Med. Assoc., 12:255-260, 1964.
15. WORLD HEALTH ORGANIZATION. EXP ERT COMMITTEE. Criteria laid down for diabetes mellitus. Washington, D.C., n° 310, 1965.

Received for publication July, 1979
Dr. Pranesh Nigam, Lecturer in Medicine, IV/18, MLB Medical College Campus, JHANSI-284001. INDIA

This journal is licensed under a Creative Commons Attribution 4.0 International License.

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