Diabetic status in leprosy

Pranesh NIGAM; S. G. DAYAL; P. SRIVASTAVA; L . D. JOSHI; B. M. GOYAL; Brahma DUTT; M. C. GUPTA

doi:10.47878/hi.1979.v4.35626

Authors

Pranesh NIGAM Lecturer in Medicine, Jhansi, India.
S. G. DAYAL Lecturer in Dermato-venereology & Leprosy, Jhansi, India.
P. SRIVASTAVA Lecturer in Biochemistry, Jhansi India.
L . D. JOSHI Reader in Biochemistry, Jhansi, India.
B. M. GOYAL Reader in Tuberculosis & Chest Diseases, Jhansi, India.
Brahma DUTT Professor & Head of the Dept. of Physiology, Jhansi, India.
M. C. GUPTA Professor & Head of the Dept. of Medicine. Jhansi, India.

DOI:

https://doi.org/10.47878/hi.1979.v4.35626

Keywords:

Diabetes, Hanseniasis, Hansen's disease, Leprosy

Abstract

The diabetic status of the local Jhansi patients (120 cases) was established before and after antileprosy treatment. Control studies were performed in normal healthy subjects (50 persons) without family history of diabetes mellitus. Random normals showed an incidence of diabetes only 2%, while leprosy patients (94 males and 26 females) had incidence of diabetic status of 14.2%. The highest incidence (19.3 %) of diabetes was in lepromatous leprosy and lowest incidence (6.4%) in tuberculoid leprosy patients. Repeated studies in leprosy after treatment showed not only clinical improvement for leprosy but also disappearance of the chemical and latent diabetes mellitus and lowering of blood sugar levels in manifest diabetes mellitus. Incidently it was noted that `diabetic status' was worse among males (82.3%) and with advancing age. Association and improvement of diabetic status with specific treatment would tentatively suggest that Mycobacterium leprae lesions are not confined to skin alone but somehow also related to carbohydrate metabolism. A careful management of the chemical and latent diabetes may help in clinical management of leprosy too.

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Received for publication July, 1979
Dr. Pranesh Nigam, Lecturer in Medicine, IV/18, MLB Medical College Campus, JHANSI-284001. INDIA