Keywords
Hanseniasis
Immunology
Immunochemistry
Rubino's reaction
Electrophoresis
Immunoelectrophoresis
Immunoglobltlins
Radial immunodiffusion
Immunology
Immunochemistry
Rubino's reaction
Electrophoresis
Immunoelectrophoresis
Immunoglobltlins
Radial immunodiffusion
How to Cite
1.
SILVA OP, FERRI RG, MORAES N, MARQUES ALV. Estudos imunoquimicos na hanseníase. III. Pesquisa de auto-anticorpos séricos. Tentativa de associação com a reação de Rubino. Hansen. Int. [Internet]. 1976 Nov. 30 [cited 2024 Nov. 22];1(2):120-4. Available from: https://periodicos.saude.sp.gov.br/hansenologia/article/view/36032
Abstract
Sera of hanseniasis patients were classified as Rubino- sitive (virchowiana) and Rubino-negative (virchowians and tuberculoids), and analysed for the presence of auto-antibodies (anti-thyreoglobulin and rheumatoid factor). The presence of anti-thyreoglobulin antibodies could be demonstrated only in virchowian Rubino-
positive patients (43%). The rheumatoid factor was detected in the two virchowian groups: 30% in the Rubino-positive and 17% in the Rubino-negative. This difference was not statistically significant.
References
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2. BONOMO, L. & DAMMACCO, F. Immune complex cryoglobulinaemia in lepromatons leprosy: a
pathogenetic approach to some clinical features of leprosy. Clin. Exp. Immunol., 9: 175-181, 1971.
4. BONOMO, L.; DAMMACCO, F.; MENEGHINI, C.; LOSPALLUTO, M. Cryoglobulinemia in lepromatous leprosy: an immune complex phenomenon. Int. J. Lepr., 39:554-556, 1971.
6. BONOMO, L; DAMMACCO, F.; PINTO, L.; BARBIERI, G. Thyroglobulin antibodies in leprosy. Lancet, 2:807-809, 1963.
5. BONOMO, L.; PINTO, L.; TURSI, A.; 11. BARBIERI, G.; DAMMACCO, F. Autoimmune reactions and macroglobulins in leprosy. Derm. int., 6: 214-215,1967.
6. CATHCART, E. S.; WILLIAMS JR., R. C.; ROSS, H. sister; CALKINS, E. The relationship of the latex fixation
test to the clinical and serological manifestations of leprosy. Amer. J.Med., 81:768-766, 1961.
7. HACKETT. E.; BEECH, M.; FORBES, I. J. Thyroglobulin antibodies in patients without clinical disease of
the thyroid gland. Lancet, 2:402-404,1960.
8. MATTHEWS, L. J. & TRAUTMAN, J. R. Clinical and serological profiles in leprosy. Lancet, 2:915-918, 1965.
9. MORAES, N. & LOPES, E. S. Introdução d bioestatística. Bauru, Fac. Odontologia, 1972.
10. PINTO, L. & BARBIERI, G. La sieropositività reumatoide nella lebbra. G. Mal. Infett., 16:466-462, 1964.
11. RIZZI, D.; DANIELLE, F.; MARANO, R. Alterazioni siero-immunitarie nella lebbra. G. Mal. Infett., 14:70-86, 1962.
12. ROSS, H., sister & PETRIE, I. M. Proteinbound iodine of the blood serum in leprosy. Int. J. Lepr., 26:122-125,
1957.
13. RUBINO, M. C. Séro-diagnostic de la lèpre par 1'agglutino-sedimentation des globules de mouton formolés.
Ann. Inst. Pasteur, 47:147-172, 1931.
14. SHULMAN, S. & WITEBSKY, E. The thyroid gland as a source and target in autosensitization. Ann. N. Y.
Acad. Sci., 86:400-416, 1960.
15. SILVA, O. P.; FERRI, R. G.; MORAES, N.; MARQUES, A. L. V. Estudos imunoquimicos na hanseniase.
II. Quantificação de imuneglobulinas séricas. Tentativa de associação com a reação de Rubino. Hansen. Int., 1(1) :43-62, 1975.
16. WAALER, E.; TONDER, O. GODAL, T.; MILDE, E. J.; SAGHER. F.; SHESKIN, J. Anti-s-globulin activity in leprous lesions. Int. J. Lepr. 89:529-540, 1971.
2. BONOMO, L. & DAMMACCO, F. Immune complex cryoglobulinaemia in lepromatons leprosy: a
pathogenetic approach to some clinical features of leprosy. Clin. Exp. Immunol., 9: 175-181, 1971.
4. BONOMO, L.; DAMMACCO, F.; MENEGHINI, C.; LOSPALLUTO, M. Cryoglobulinemia in lepromatous leprosy: an immune complex phenomenon. Int. J. Lepr., 39:554-556, 1971.
6. BONOMO, L; DAMMACCO, F.; PINTO, L.; BARBIERI, G. Thyroglobulin antibodies in leprosy. Lancet, 2:807-809, 1963.
5. BONOMO, L.; PINTO, L.; TURSI, A.; 11. BARBIERI, G.; DAMMACCO, F. Autoimmune reactions and macroglobulins in leprosy. Derm. int., 6: 214-215,1967.
6. CATHCART, E. S.; WILLIAMS JR., R. C.; ROSS, H. sister; CALKINS, E. The relationship of the latex fixation
test to the clinical and serological manifestations of leprosy. Amer. J.Med., 81:768-766, 1961.
7. HACKETT. E.; BEECH, M.; FORBES, I. J. Thyroglobulin antibodies in patients without clinical disease of
the thyroid gland. Lancet, 2:402-404,1960.
8. MATTHEWS, L. J. & TRAUTMAN, J. R. Clinical and serological profiles in leprosy. Lancet, 2:915-918, 1965.
9. MORAES, N. & LOPES, E. S. Introdução d bioestatística. Bauru, Fac. Odontologia, 1972.
10. PINTO, L. & BARBIERI, G. La sieropositività reumatoide nella lebbra. G. Mal. Infett., 16:466-462, 1964.
11. RIZZI, D.; DANIELLE, F.; MARANO, R. Alterazioni siero-immunitarie nella lebbra. G. Mal. Infett., 14:70-86, 1962.
12. ROSS, H., sister & PETRIE, I. M. Proteinbound iodine of the blood serum in leprosy. Int. J. Lepr., 26:122-125,
1957.
13. RUBINO, M. C. Séro-diagnostic de la lèpre par 1'agglutino-sedimentation des globules de mouton formolés.
Ann. Inst. Pasteur, 47:147-172, 1931.
14. SHULMAN, S. & WITEBSKY, E. The thyroid gland as a source and target in autosensitization. Ann. N. Y.
Acad. Sci., 86:400-416, 1960.
15. SILVA, O. P.; FERRI, R. G.; MORAES, N.; MARQUES, A. L. V. Estudos imunoquimicos na hanseniase.
II. Quantificação de imuneglobulinas séricas. Tentativa de associação com a reação de Rubino. Hansen. Int., 1(1) :43-62, 1975.
16. WAALER, E.; TONDER, O. GODAL, T.; MILDE, E. J.; SAGHER. F.; SHESKIN, J. Anti-s-globulin activity in leprous lesions. Int. J. Lepr. 89:529-540, 1971.
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