Abstract
The author compares the therapeutic results of Rifampicin and DDS in eight twins (plus one father), suffering from hanseniasis (leprosy). Both the improvement of the cutaneous lesions and the bacilloscopic decrease, were much quicker with the Rafampicin, in all cases except one, in which the Rifampicin did not act. The patients were observed at least for eight months, and showed no important side-effects. The DDS doses ranged from 60 to 100 mg daily and the Rifampicin doses varied from 460 to 600 mg daily.
References
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2. BARBOSA, A. A rifampicina (Rifadin) no tratamento da lepra. Rovisco Pais: rev. port. doença Hansen, 12(1):8-86, 1978.
3. CHANALET, G.; GUYON, J.; BEAUTE, J.; PARC, F.; BOUTIER, F. Premiers résultats du traitement de la lèpre en Nouvelle Calédonie par la rifampicine. Med. Trop., 32(2): 203-215, 1972.
4. DOURADO, H. V.; BORBOREMA, C. A. T.; ALECRIM, W.; TALHARI, SLeishmaniase tegumentar americana:
tratamento com rifampicina. Rev. Bras. Clin. Terap. 4(1): 1-6, 1975.
5. LANGUILLON, J. Activité de dens antituberculeux: la rifampicine et l'ethambutal dane la maladie de Hansen. Acta Leprol., (46/47) :123-131, 1972.
6. OPROMOLLA, D. V. A. & ALMEIDA, S. C. Primeiros resultados no tratamento da lepra com a kanamicina. Rev. Bras. Leprol., 87:17-89, 1970.
8. SERAFINO, A. & SILVESTRE, N. Ensayos preliminares del uso de la rifamacine en la lepra. Semana Med., 142(7):258-259, 1978.
9. WILKINSON, F. F.; GAGO, J.; SANTABAYA, E. Therapy of leprosy with rifampicin. Int. J. Lepr., 40 (1):58-57, 1972.
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