Perfil de las isoenzimas de la dehidrogenasa láctica en el suero de pacientes hansenianos

Authors

  • Roberto Garcia Departamento de Política Científica y Tecnológica, Universidad Nacional de Luján, Casilla 221, (6700) Luján (B), Buenos Aires, Argentina.
  • Alfredo Salibian Departamento de Política Científica y Tecnológica, Universidad Nacional de Luján, Casilla 221, (6700) Luján (B), Buenos Aires, Argentina. Carrera del Investigador Científico y Tecnológico, Comisión de Investigaciones Científicas (C.I.C.), Buenos Aires, y Universidad Nacional de Lomas de Zamora, Buenos Aires.
  • Berta Llorente Departamento de Política Científica y Tecnológica, Universidad Nacional de Luján, Casilla 221, (6700) Luján (B), Buenos Aires, Argentina.
  • Ana Pacin Departamento de Política Científica y Tecnológica, Universidad Nacional de Luján, Casilla 221, (6700) Luján (B), Buenos Aires, Argentina.
  • Enrique L. Fliess Departamento de Política Científica y Tecnológica, Universidad Nacional de Luján, Casilla 221, (6700) Luján (B), Buenos Aires, Argentina. Sanatorio Nacional "Baldomero Sommer", Buenos Aires.

DOI:

https://doi.org/10.47878/hi.1980.v5.36106

Keywords:

Hanseniasis, Enzymes, Isoenzymes, LDH isoenzymes

Abstract

The LDH isoenzymes levels in fresh serum of seven patients affected by different forms of hanseniasis from Argentina, were measured by acrylamide electrophoresis. In all cases the LDH-4 fraction was found elevated; on the contrary, I,DH-2 was reduced. The LDH-5 fraction was detected in only three serums, all of them
significantly increased when compared with controls.

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References

AGARWAL, D.P.; SRIVASTAVA, L.M.; GOEDDE, H.W.; ROHDE, R. 1975. Biochemical immunological and genetic studies in leprosy. I. Changes in serum lactate dehydrogenase isoenzymes, creatine phosphokinase and aldolase activity in different forms of leprosy. Tropenmed. Parasit., 26(2) :207-211.
DIETZ, A.A. & LUBRANO, T. 1967. Separation and quantitation of lactic dehydrogenase isoenzymes by disc electrophoresis. Anal. Biochem., 20:246-257.
LEVITCH, M.E. & NAVALKAR, R.G. 1970. Serum lactic dehydrogenase isoenzymes in leprosy. Int. J. Lepr., .98(4):368-372.
LLORENTE, B.; FLIESS, E.L.; GARCIA, R.; PACIN, A.; SALIBIAN, A. (s.f.) Perfil enzimológico de la hanseniasis. Revisión crítica. Leprologia [en prensa]
SAITO, N. 1972. Lactic dehydrogenase isoenzymes in leprosy patients. I. Serum lactic dehydrogenase. Lepr. India, 44(2) :82-89.

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Published

1980-11-30

How to Cite

1.
Garcia R, Salibian A, Llorente B, Pacin A, Fliess EL. Perfil de las isoenzimas de la dehidrogenasa láctica en el suero de pacientes hansenianos. Hansen. Int. [Internet]. 1980 Nov. 30 [cited 2024 May 18];5(2):119-22. Available from: https://periodicos.saude.sp.gov.br/hansenologia/article/view/36106

Issue

Vol. 5 No. 2 (1980)

Section

Original articles

License

Creative Commons License

This work is licensed under a Creative Commons Attribution 4.0 International License.

This journal is licensed under a Creative Commons Attribution 4.0 International License.