Abstract
A 31 years old man looked for specialized health service due to sensibility changes in his left arm. Clinical examination confi rmed this complaint. Skin smears collected from the altered area did not show acid-fast bacilli. Mitsuda reaction was negative and a biopsy from the skin did not show any bacilli or infl ammatory process. The diagnosis was indeterminate (early) leprosy, and multidrugtherapy for paucibacillary leprosy was started. Nine years later, he returns with several lesions characteristics of borderline leprosy, which was confi rmed by skin biopsy and bacilloscopy of skin
smears. The previous treatment may have not destroy all the bacilli. In this situation remnant bacilli could have replicated, slowly and rogressively, reproducing the large period of incubation typical of individuals with negative Mitsuda reaction. Limitations of diagnosis based only in clinical features and in the lesions count criteria are discussed.
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