Histogenic differentiation of polar tuberculoid granuloma and the "benign" or "malignant" behaviour of hanseniasis

Jorge MICHALANY; Nílceo S. MICHALANY

doi:10.47878/hi.1989.v14.36495

Authors

Jorge MICHALANY From the Departament of Pathological Anatomy Escola Paulista de Medicina - Paulo, SP - Brazil
Nílceo S. MICHALANY From the Departament of Pathological Anatomy Escola Paulista de Medicina - Paulo, SP - Brazil.

DOI:

https://doi.org/10.47878/hi.1989.v14.36495

Keywords:

Hanseniasis, Histogenetic di fferent iation, Polar tuberculoid granuloma, Granulomatous inflammation

Abstract

B a s e d o n a n ew mo r p h o l o g i c a l c o n c e p t a n d c l a s s i f i c a t i o n o f
granulomatous inflammation: the polar granulomas, on the histogenesis of the tuberculoid
granuloma of the posi t ive Mi tsuda test and on the relat ionship between the degree of
histogenetic differentiation and behaviour of tumors, the Authors concluded that the "benign" or
"malignant" behaviour of hanseniasis depends on the degree of tuberculoid differentiation of the
lesions. If the lesion is histologically well differentiated toward a polar tuberculoid granuloma
(tuberculoid hanseniasis) it will have a "benign" behaviour. On the contrary, if this
differentiation is absent (virchowlan hanseniasis) or poor (interpolar bordeline hanseniasis)
the behaviour of the lesion will be "malignant".

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References

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