Keywords
hamster
M.bovis BCG
M.tuberculosis
M.bovis BCG
M.tuberculosis
How to Cite
1.
Roxo E, Sinhorini IL, Mariano M. Evolução das lesões induzidas por micobactérias BCG e por H37RV em hamster (Mesocricetus auratus). Hansen. Int. [Internet]. 1994 Nov. 30 [cited 2024 Nov. 22];19(2):19-25. Available from: https://periodicos.saude.sp.gov.br/hansenologia/article/view/36508
Abstract
Some aspects of the pathogeny of tuberculosis was experimentally investigated by inoculating either an attenuated mycobacteria strain - BCG or a virulent strain - M.tuberculosis H37Rv into the foot pad or the cheek pouch of hamster. The inoculation of these agents determined different
patterns of lesion. The BCG-induced lesions in the foot pad had a tendency to decrease in size. On the other hand, the lesions by H37Rv showed a progressive evolution. The same pattern of evolution was observed with the lesions induced in the cheek pouch. However, the H37Rv disseminated to internal organs and the BCG did not.
References
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13. STEENKEN, W. Jr.; OATWAY, W.H. Jr.; PETROFF, S.A. Biological studies of the tubercle bacillus. II. Dissociation and pathogenicity of the R and S variants of the human tubercle bacillus (H"). J.Exp.Med., 60(2): 515-540, 1934.
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2. BARKER, C.F.; BILLINGHAM, R.E. Immunologically privileged sites. Advances in Immunology, 25: 1-54, 1977.
3. BARKSDALE, L.; KIM, L.S. Mycobaterium. Bacteriological Reviews, 41(1): 217-372, 1977.
5. BUENO, P. Estudos sobre a causa da necrose no processo tuberculoso. Rev.Bras.Tub., 31(149): 835-842, 1953.
7. BUNCH-CHRISTENSEN, K.; LADEFOGED, A.; GUID, J. The virulence of some strains of BCG for golden hamster. Bull. Org. Mond. Santé, 43: 65-70, 1970.
8. DENNIS, E.W.; GOBLE, F.C.; BERBERIAN, D.A. ; FRELIH, E.J . Exper imental tuberculosis of the syrian hamster (Cricetus auratus). Annals N.Y. Academy of Sciences, 52(1): 646-661, 1949.
9. LURIE, M.B.; DANNENBERG, A.M. Jr. Macrophage function in infectious disease with inbred rabbits. Bacteriological Reviews, 29(4): 466-476, 1965.
10. LURIE, M.B.; ZAPPASODI, P.; TICKNER, C. On the nature of genetic resistance to tuberculosis in the light of the host-parasite relationships in natively resistant and susceptible rabbits. Am. Rev. Resp. Dis., 2(3): 297-323, 1955.
9. MARIANO, M. The experimental granuloma. (dados não publicados).
10. MEDAWAR, P.B. Immunity to homologous grafted skin. Ill. The fate of skin homografts transplanted to the brain, to subcutaneous tissue, and to the anterior chamber of the eye. Brit. J. exp. Path. London, 29: 58-69, 1948.
11.RATLEDGE, G.; STANFORD, J. The biology of mycobacteria, ed. 2, Acad. Press. London, 1982. 1(2): 544.
12. SINHORINI, I.L. Formação do granuloma induzido pelo BCG no hamster. Influência do "PPD” na evolução das lesões. São
Paulo, 1983. p. (Tese de Doutoramento/Faculdade de Medicina Veterinária e Zootecnia/USP).
13. STEENKEN, W. Jr.; OATWAY, W.H. Jr.; PETROFF, S.A. Biological studies of the tubercle bacillus. II. Dissociation and pathogenicity of the R and S variants of the human tubercle bacillus (H"). J.Exp.Med., 60(2): 515-540, 1934.
14. YOUMANS, G.P. Tuberculosis. 1 ed. Philadelphia. W.B. Saunders Company, 1979, 511p.
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