Evolução das lesões induzidas por micobactérias BCG e por H37RV em hamster (Mesocricetus auratus)

Eliana Roxo; Idércio Luiz Sinhorini; Mário Mariano

doi:10.47878/hi.1994.v19.36508

Authors

Eliana Roxo Pesquisadora Cientifica, Chefe da Seção de Patologia Clinica - Instituto Biológico - Sao Paulo
Idércio Luiz Sinhorini Prof. Dr. - Depto. Patologia da Fac. Med. Vet. Zoot. - Univ. São Paulo
Mário Mariano Prof. Titular - Depto. Imunopatologla - Inst. Biociências - Univ. São Paulo.

DOI:

https://doi.org/10.47878/hi.1994.v19.36508

Keywords:

hamster, M.bovis BCG, M.tuberculosis

Abstract

Some aspects of the pathogeny of tuberculosis was experimentally investigated by inoculating either an attenuated mycobacteria strain - BCG or a virulent strain - M.tuberculosis H37Rv into the foot pad or the cheek pouch of hamster. The inoculation of these agents determined different
patterns of lesion. The BCG-induced lesions in the foot pad had a tendency to decrease in size. On the other hand, the lesions by H37Rv showed a progressive evolution. The same pattern of evolution was observed with the lesions induced in the cheek pouch. However, the H37Rv disseminated to internal organs and the BCG did not.

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